
Extravillous trophoblast - Wikipedia
Extravillous trophoblast (EVT) cells migrate from anchoring villi, and invade into the decidua basalis. Their main function is remodelling the uterine spiral arteries, to achieve an increase in …
Extravillous trophoblast cell lineage development is ... - Nature
2023年8月10日 · EVT cells are terminally differentiated trophoblast cells that invade into and restructure the uterine compartment, including transforming tightly coiled spiral...
Single-cell RNA-seq reveals the diversity of trophoblast ... - Nature
2018年7月24日 · New subtypes of cells of the known cytotrophoblast cells (CTBs), extravillous trophoblast cells (EVTs), Hofbauer cells, and mesenchymal stromal cells were identified and...
Spatial multiomics map of trophoblast development in early
2023年3月29日 · Extravillous trophoblast cells (EVTs) derived from placental villi infiltrate the decidua, transforming the maternal arteries into high-conductance vessels 1. Defects in...
如何建立人胎盘滋养层类器官, Nature Protocols (2020) - 知乎
一旦去除所有生长因子和WNT激活剂,但保持TGFβ抑制,并添加NRG1(Neuregulin 1),我们就能够有效地从类器官中产生EVT。添加NRG1是基于报告显示蜕膜衍生的NRG1促进胎盘外植 …
单细胞测序揭示人胎盘内皮细胞及滋养细胞的异质性和分化 - 知乎
2023年3月1日 · Result6 人类滋养细胞祖细胞有助于EVT分化 VCT-3作为一个活跃的增殖亚群(图4E),具有VCT到EVT分化的基因表达特征(图4D和5A)。 因此作者通过免疫荧光和染色( …
NOTUM-mediated WNT silencing drives extravillous trophoblast cell ...
2024年9月26日 · Notum, palmitoleoyl-protein carboxylesterase (NOTUM), a negative regulator of canonical WNT signaling, was prominently expressed in first-trimester EVT cells developing in …
Single-cell characterization of self-renewing primary trophoblast ...
2023年10月18日 · EVT, derived from villous cytotrophoblast (CTB) through cytotrophoblast cell column (CCC), has unique human leucocyte antigen (HLA) expression profile (positive for HLA …
The autophagy process and oxidized LDL independently modulate …
2024年12月1日 · Here, we studied the effect of modulating autophagy and ox-LDL in a model of EVT cells (HTR-8/SVneo) and we demonstrated that autophagy is essential for the acquisition …
The term basal plate of the human placenta as a source of …
2014年1月28日 · Term basal plate may be a viable source of functional EVT cells that is an alternative to villous explant-derived EVT cells and cell lines. Isolated term EVT cells may be …
- 某些结果已被删除