2024年8月23日 · Exemestane (brand name Aromasin) is an aromatase inhibitor used to lower estrogen levels in women past menopause with early or advanced hormone-sensitive breast cancer. Early breast cancer is cancer that has not spread outside the breast. Advanced breast cancer is cancer that has spread to other parts of the body.

Exemestane is an irreversible, steroidal aromatase inactivator of type I, structurally related to the natural substrate 4-androstenedione. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as " suicide ...

2024年8月19日 · Exemestane belongs to a class of medicines called aromatase inhibitors. It works by blocking an enzyme called aromatase that helps produce estrogen in the body. By lowering the amount of...

Exemestane is used to treat early and advanced breast cancer in women who have already stopped menstruating (postmenopausal). It is usually used in women who have already received a cancer medication called tamoxifen. Many breast cancer tumors grow in response to estrogen. Exemestane interferes with the production of estrogen in the body.

依西美坦，化学名称为6-亚甲基雄甾-1,4-二烯-3,17-二酮，是一种有机化合物，化学式为C20H24O2，为白色至淡黄色结晶性粉末，溶于甲醇，不溶于水，是一种抗肿瘤药，临床上适用于以他莫昔芬治疗后病情进展的绝经后晚期乳腺癌患者。 化学式：C20H24O2. 分子量：296.403. CAS号：107868-30-4. 密度：1.13 g/cm 3. 熔点：155.1°C. 沸点：453.7ºC. 闪点：169ºC. 折射率：1.572. 外观：白色至淡黄色结晶性粉末. 溶解性：溶于甲醇，不溶于水 [1] 摩尔折射 …

Exemestane is an antineoplastic (anticancer) agent used to treat breast cancer in postmenopausal women. Exemestane is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox) for 2 to 3 years.

依西美坦 （INN: exemestane，商品名Aromasin，台灣譯名諾曼癌素）是治療 乳癌 的抗雌激素藥物，屬於芳香化酶抑制劑。 某些乳癌細胞具有雌激素 受体 （ER），受 雌激素 刺激而生長，被稱為ER陽性（或稱雌激素反應性、激素反應性或激素受體陽性乳癌）。 芳香化酶 是合成雌激素的 酶，使用其抑制劑可阻止雌激素的合成，以減緩腫瘤的生长。 依西美坦的適應症是治療停經後雌激素受體陽性早期乳癌病人，術後曾接受過tamoxifen治療二至三年，可轉用本藥完成共計五年的 …

2023年5月22日 · Learn about the side effects of exemestane, from common to rare, for consumers and healthcare professionals.

Exemestane is indicated for the adjuvant treatment of postmenopausal women with estrogen-receptor positive or unknown early breast cancer to reduce the risk of recurrence (distant and loco-regional) and contralateral breast cancer.

View exemestane information, including dose, uses, side-effects, renal impairment, pregnancy, breast feeding and contra-indications.