
【讨论】α-actin、β-actin和F-actin、G-actin的区别和联系
2007年10月25日 · Actin大致可分为六种,其中四种是不同肌肉组织特异性的,包括α-skeletal muscle actin,α-cardiac muscle actin,α-smooth muscle actin,和γ-smooth muscle actin;其余两种广泛分布于各种组织中,包括β-actin (β-non-muscle)和γ-non-muscle actin。 不同的actin之间同源性大于90%,但在N-terminal同源性仅50--60%,因此N-terminal常被用作actin的抗原。 β-actin的蛋白水平通常不会发生改变,因此被广泛用于Western时上样量是否一致的参照。 也常 …
Actin - Wikipedia
Under various conditions, G-actin molecules polymerize into longer threads called "filamentous-" or "F-actin". These F-actin threads are typically composed of two helical strands of actin wound around each other, forming a 7 to 9 nanometer wide helix that repeats every 72 nanometers (or every 14 G-actin subunits). [101] In F-actin threads, G ...
Actin:细胞骨架的核心成分与多功能蛋白
2025年1月13日 · 在细胞内,Actin主要以单体(G-Actin)和多聚体(F-Actin)两种形式存在。 单体形式的Actin具有球形结构,而多聚体形式的Actin则通过头尾相连的方式形成螺旋状的长丝,这些长丝进一步交织成复杂的网络结构,构成了细胞骨架的主要部分。
肌动蛋白 - 维基百科,自由的百科全书
肌动蛋白可以作为称为g-肌动蛋白 (球状)的游离单体存在,或作为称为f-肌动蛋白(丝状)的线性聚合物微丝的一部分存在,这两者对于细胞的移动和收缩等重要的细胞功能是必不可少的。
F Actin - an overview | ScienceDirect Topics
F-actin, in the field of neuroscience, refers to a crucial component of the cytoskeleton found in dendritic filopodia and spines. It plays a significant role in regulating spine morphogenesis and synaptic plasticity.
F-actin architecture determines the conversion of chemical energy …
2024年4月24日 · Actin filaments (F-actin) are in a non-equilibrium dynamic steady-state, continuously undergoing assembly and disassembly of actin monomers (G-actin), termed turnover, which is sustained by...
丝状肌动蛋白的组装及其生物学功能-SciEngine
丝状肌动蛋白(filamentous actin,F-actin)是细胞骨架的组分之一,是由球状单体肌动蛋白(globular actin,G-actin)组装而成的多聚体。 细胞中的F-actin聚合过程复杂而有序,并处于动态平衡。
Afadin mediates cadherin-catenin complex clustering on F-actin …
2025年2月14日 · Mechanical force and auxiliary binding partners converge to stabilize the cadherin-catenin complex’s inherently weak binding to actin filaments (F-actin) through unclear mechanisms. Here, we show that afadin’s coiled-coil (CC) domain and vinculin synergistically enhance the cadherin-catenin complex’s F-actin engagement.
Actin Structure and Function - PMC - PubMed Central (PMC)
ATP-bound G-actin is the normal substrate for filament formation. It may be induced to polymerize to ATP-containing F-actin, which is energetically favored under physiological conditions. However, F-actin is a slow ATPase, such that the filament soon contains just ADP. ADP F-actin is less stable than ADP G-actin.
【专题讨论】F-actin与β-actin - 丁香园论坛 - DXY.cn
细胞中actin存在两种形式,一种是单体的G-actin,一种是多聚体F-actin。 (这些都来自维基百科) 那么这里的γ-actin应该是gamma-actin的意思,G-actin(globular actin)是肌球蛋白,γ-actin与G-actin好像应该是不同的吧,但是在NCBI中搜到的结果却是相同,γ-actin与G-actin到底是不是同一个呢? 另外一个问题,nature cell biology上有篇文献报道进行血清饥饿的时候,观察F-actin,显示变少,说对细胞骨架有影响,但是下文在寻找下游调控时的western中却用actin(文章中没 …
- 某些结果已被删除