2022年8月23日 · Factor V Leiden (FAK-tur five LIDE-n) is a mutation of one of the clotting factors in the blood. This mutation can increase your chance of developing abnormal blood clots, most commonly in your legs or lungs. Most people with factor V Leiden never develop abnormal clots.

Factor V Leiden is an inherited blood clotting disorder that raises your risk of deep vein thrombosis or a pulmonary embolism. A mutation in the F5 gene causes it.

Coagulation factor V (Factor V), also less commonly known as proaccelerin or labile factor, is a protein involved in coagulation, encoded, in humans, by F5 gene. [5] In contrast to most other coagulation factors, it is not enzymatically active but functions as a cofactor. [5]

The F5 gene provides instructions for making a protein called coagulation factor V. Learn about this gene and related health conditions.

5 天之前 · F5 (Coagulation Factor V) is a Protein Coding gene. Diseases associated with F5 include Factor V Deficiency and Thrombophilia Due To Activated Protein C Resistance. Among its related pathways are Diseases of hemostasis and Transport to …

2024年5月6日 · The F5 gene, situated on chromosome 1q24.2 and spanning 25 exomes, consists of 6 domains: A1, A2, A3, B, C1, and C2. Sequencing deoxyribonucleic acid from peripheral blood leukocytes helps identify mutations within this gene to diagnose inherited factor V deficiency.

2024年10月13日 · Factor V (factor 5) is one of several special proteins in your blood that help it clot. They're called clotting factors. Once the bleeding stops, other proteins tell your clotting factors to break...

2025年3月16日 · The F5 gene is responsible for making a protein called coagulation factor V. This protein is essential for blood clotting. Changes in the F5 gene affect clotting. Some changes can cause too much bleeding, while others may increase the chance of getting blood clots.

2011年12月13日 · The F5 gene encodes coagulation factor V, a large 330-kD plasma glycoprotein that circulates with little or no activity. Factor V is converted to the active form, factor Va, by thrombin (F2; 176930), which generates a heavy chain and …

The F5 gene provides instructions for making a protein called coagulation factor V. This protein plays a critical role in the coagulation system, which is a series of chemical reactions that forms blood clots in response to injury.