Central retinal artery occlusion (CRAO) is a form of acute ischemic stroke that results in painless vision loss attributable to retinal infarction. A keen understanding of clinical presentation and underlying pathophysiological features is key to timely intervention and development of new treatment modalities.

It is an obstruction of retinal blood flow that may be due to an embolus causing occlusion or thrombus formation, vasculitis causing retinal vasculature inflammation, traumatic vessel wall damage, or spasm. The lack of oxygen delivery to the retina during the blockage often results in severe vision loss in the area of ischemic retina.

2023年10月25日 · Although FA is currently still the gold standard for diagnosing CRAO, the invasive and time-consuming nature of FA often delays the treatment of CRAO. In this study, we found that patients without cherry-red spots had a higher number of cases with normal arteriovenous transit time (< 15 s) and a lower number of cases with delayed arteriovenous ...

2024年3月28日 · Central retinal artery occlusion (CRAO), like a stroke in the brain, is a critical eye condition that requiring urgent medical attention. Patients with CRAO...

2022年12月28日 · In a study by Gong et al., three types of CRAO were identified on FA, viz. poor perfusion, exudation and mixed patterns based on the arm-retina time and retina vascular leakage [4]. These...

Visual acuity testing, evaluation for an afferent pupillary defect, funduscopic examination, and fluorescein angiography (FA) remain the mainstay tools for diagnosing central retinal artery occlusion.

2019年7月10日 · In the clinic, fluorescein angiography (FA) is applied to visualize retinal vessels and evaluate the vessel flow in RAO patients. However, capillary networks in different layers of the retina cannot be distinguished or quantified by FA. In addition, FA is an invasive examination; thus, its frequent application is limited.

2025年2月1日 · To characterize a large modern cohort of patients with central retinal artery occlusion (CRAO) by describing presenting features and outcomes relating to manually segmented optical coherence tomography (OCT) features, …

2019年1月3日 · Incomplete CRAO is characterized by diminished VA, slight retinal edema with indefinite cherry-red spots, and mildly delayed retinal arterial perfusion on fluorescein angiography (FA). Subtotal CRAO is identified as severe reduction in VA, distinct retinal edema with cherry-red spots, and severely delayed retinal arterial perfusion.

2024年5月2日 · Central retinal artery occlusion (CRAO) is an ophthalmic emergency that can lead to sudden and severe vision loss. CRAO has been defined as interruption of blood flow through the central retinal artery by thromboembolism or vasospasm with or without retinal ischemia.