
Fructose-1,6-bisphosphatase inhibitors: A new valid approach …
2017年12月1日 · Fructose-1,6-bisphosphatase (FBPase), a well recognized rate controlling enzyme of gluconeogenesis, has emerged as legitimate molecular level target to control …
Fructose-1,6-Bisphosphatase Deficiency - GeneReviews® - NCBI Bookshelf
2019年12月5日 · Fructose-1,6-bisphosphatase 1 (FBPase, or FBP1) is a key enzyme of the gluconeogenic pathway. Its deficiency impairs glucose production from all gluconeogenic …
Fructose-1,6-bisphosphatase: From a glucose metabolism …
2019年5月1日 · Fructose-1,6-bisphosphatase (FBPase) is one of the ancient, evolutionarily conserved enzymes of carbohydrate metabolism. It has been described for a first time in 1943, …
Fructose 1,6-bisphosphatase - an overview - ScienceDirect
Fructose-1,6-bisphosphatase (FBPase) is a cytosolic enzyme, and two isoforms of FBPase have been reported in mammals encoded by two genes: a liver FBPase (FBP1), which is expressed …
Fructose 1,6-bisphosphatase: getting the message across - PMC
Fructose 1,6-bisphosphatase (FBPase) is a key enzyme in gluconeogenesis. It is a potential drug target in the treatment of type II diabetes. The protein is also associated with a rare inherited …
Cytosolic fructose-1,6-bisphosphatase: A key enzyme in the
Fructose-1,6 bisphosphatase (FBPase) is a ubiquitous enzyme controlling a key reaction. In non-photosynthetic tissues, it regulates the rate of gluconeogenesis. In photosynthetic tissues, two …
Fructose-1, 6-bisphosphatase inhibitors for reducing excessive ... - PubMed
Fructose-1,6-bisphosphatase (FBPase), a rate-controlling enzyme of gluconeogenesis, has emerged as an important target for the treatment of type 2 diabetes due to the well-recognized …
Characterization of recombinant fructose-1,6-bisphosphatase …
2019年2月2日 · Fructose-1,6-bisphosphatase (FBPase) is a complex tetramer and a highly regulated enzyme. FBPase activity is regulated synergistically by the allosteric inhibitors AMP …
Identification of genotype–biochemical phenotype correlations ...
2023年7月28日 · Fructose-1,6-bisphosphatase (FBPase) deficiency, caused by an FBP1 mutation, is an autosomal recessive disorder characterized by hypoglycemic lactic acidosis. …
Cytosolic fructose-1,6-bisphosphatase: A key enzyme in the …
Fructose-1,6 bisphosphatase (FBPase) is a ubiquitous enzyme controlling a key reaction. In non-photosynthetic tissues, it regulates the rate of gluconeogenesis. In photosynthetic tissues, two …
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