Oct 10, 2024 · MRI is the modality of choice to assess patients with possible focal cortical dysplasias although not all histopathological proven areas of focal cortical dysplasia will be evident on MRI and at other times FCD will be found adjacent to other lesions (e.g. tumors) 11.

Focal cortical dysplasia (FCD) are histopathologically categorized in ILAE type I to III. Mild malformations of cortical development (mMCD) including those with oligodendroglial hyperplasia (MOGHE) are to be integrated into this classification yet. Only FCD type II have distinctive MRI and molecular genetics alterations so far.

局灶性皮层发育不良 （focal cotical dysplasia，FCD）是主要累及大脑皮层的局灶性脑皮质结构异常疾病，是皮层发育畸形（malformations of cortical development, MCD）的一种。 1971年Taylor等首次描述了局灶性皮质发育不良。 FCD主要临床表现为药物难治性癫痫和局灶神经功能障碍。 且为儿童难治性癫痫最常见的原因。 主要病理改变： （1）皮质结构异常：层状结构紊乱、柱状结构紊乱、白质内和分子层神经元数目增多； （2）细胞结构异常：出现不成熟神经元、巨 …

Nov 27, 2021 · Focal cortical dysplasia (FCD) are histopathologically categorized in ILAE type I to III. Mild malformations of cortical development (mMCD) including those with oligodendroglial hyperplasia (MOGHE) are to be integrated into this classification yet. Only FCD type II have distinctive MRI and molecular genetics alterations so far.

Apr 1, 2003 · BACKGROUND AND PURPOSE: Focal cortical dysplasia (FCD) covers a spectrum of conditions in which the neuropathologic and electroclinic presentations and the surgical outcomes vary. The aim of this study was to identify the MR features of histologic subtypes of FCD that would be useful for differential diagnosis.

Sep 2, 2024 · We performed a comprehensive study by choosing six different well-known DL models, three image planes (axial, coronal, and sagittal) of two MRI modalities (T1w and FLAIR), demographic...

To characterize in vivo MRI signatures of focal cortical dysplasia (FCD) type IIA and type IIB through combined analysis of morphology, intensity, microstructure, and function. We carried out a multimodal 3T MRI profiling of 33 histologically proven ...

FCD was identified by MRI in 32 cases. Blurring of the gray-white matter junction is the most common sign of FCD (23 cases). There were 21 cases identified by MRI in FCD type Ⅰ group. Focal brain hypoplasia is a typical sign of FCD type Ⅰ , which was found in 11 cases in FCD type Ⅰ group but none in FCD type Ⅱ group.

We generated a radiomics nomogram based on multiparametric magnetic resonance imaging (MRI) to diagnose FCD and identify laterality early. Forty-three patients treated between July 2017 and May 2022 with histopathologically confirmed FCD were retrospectively enrolled. The contralateral unaffected hemispheres were included as the control group.

Focal cortical dysplasia (FCD) are histopathologically categorized in ILAE type I to III. Mild malformations of cortical development (mMCD) including those with oligodendroglial hyperplasia (MOGHE) are to be integrated into this classification yet. Only FCD type II have distinctive MRI and molecular …