Fixed-dose combination (FDC) formulations are currently recommended for the treatment of active tuberculosis (TB). We have conducted a systematic review to evaluate the risk of …

Fixed-dose combinations (FDCs) of drugs for TB treatment have been advocated internationally to prevent the emergence of drug resistance attributable to inappropriate drug intake. 10, 11 Use …

The fixed-dose combination (FDC) for first-line antituberculosis (TB) treatment has long been a standard practice worldwide; however, there is limited evidence on whether the use of FDC …

Child-friendly formulations: NTPs are encouraged to prioritize the use of child-friendly fixed dose combination (FDC) formulations for TB treatment in children up to 25 kg body weight, such as: …

WHO and other organisations recommend fixed-dose combination formulations (FDCs) as a further step to facilitate the optimal drug treatment of TB. Using FDCs in TB control will simplify …

We evaluated the efficacy and safety of FDC versus loose formulation (LF) TB treatment regimens for treatment of pulmonary TB (PTB) in the context of actual medical practice in …

2016年5月17日 · Fixed-dose combinations (FDCs) of these drugs are widely recommended. Objectives: To compare the efficacy, safety, and acceptability of anti-tuberculosis regimens …

2011年4月13日 · Few randomized trials have been conducted to assess the feasibility, safety, and efficacy of a 4-drug (rifampicin, isoniazid, pyrazinamide, ethambutol) FDC for the treatment of …

FDC formulations combine several TB drugs (2, 3 or 4) in the same tablet. FDCs are only available for first-line TB drugs. FDCs improve adherence (decreased pill burden, decreased …

The treatment for pulmonary TB in new patients includes four oral medicines taken for six months, sometimes as fixed-dose combinations (FDCs) that are combined in one tablet, or taken …