2012年9月13日 · The aim of this trial was to determine whether FFR-guided PCI with drug-eluting stents plus the best available medical therapy is superior to the best available medical therapy alone in...

2022年8月31日 · In patients with coronary artery disease who are being evaluated for percutaneous coronary intervention (PCI), procedures can be guided by fractional flow reserve (FFR) or intravascular...

2009年1月15日 · Fractional flow reserve (FFR) is an index of the physiological significance of a coronary stenosis and is defined as the ratio of maximal blood flow in a...

2023年3月4日 · TARGET is the first randomized trial to assess the effect of an on-site CT-FFR strategy using machine learning compared with standard care in patients with new-onset stable chest pain with an intermediate to high pretest of coronary artery disease probability found to have intermediate stenosis on CCTA.

Quantitative flow ratio (QFR) is an angiography-based computational method for the estimation of FFR that does not require the use of pressure wires. We aimed to investigate whether a QFR-based diagnostic strategy yields a non-inferior 12-month …

The FFR REACT study is an investigator-initiated, single-center, double-blind, parallel-arm trial that randomized patients with a post-PCI FFR <0.90 in a 1:1 ratio to IVUS-guided PCI optimization or the standard of care (the control arm [ie, the end of the procedure]) between October 31, 2017, and April 22, 2020.

2023年8月21日 · FAME 3 (Fractional Flow Reserve versus Angiography for Multivessel Evaluation) is the first randomized controlled trial comparing fractional flow reserve–guided percutaneous coronary intervention using current-generation drug-eluting stents with coronary artery bypass grafting for patients with 3-vessel coronary artery disease.

2024年11月9日 · Quantitative flow ratio (QFR) is an angiography-based computational method for the estimation of FFR that does not require the use of pressure wires. We aimed to investigate whether a QFR-based diagnostic strategy yields a non-inferior 12-month clinical outcome compared with an FFR-based strategy.

2021年11月1日 · The FUTURE trial is a prospective, randomized, open-label superiority trial. Multivessel CAD candidates were randomly assigned (1:1) to treatment strategy based on FFR in all stenotic (≥50%) coronary arteries or to a traditional strategy without FFR.

1 天前 · The authors should be congratulated for conducting this novel and comprehensive subgroup analysis of FAVOR III China that, for the first time, offers insights into the role of angiographically derived physiology in guiding revascularization of functionally intermediate lesions within the uncertainty‐zone where FFR and angiography‐derived pressure ratios such as QFR exhibit greater discordance.