2017年5月11日 · Large randomized studies have shown that fractional flow reserve (FFR) is superior to angiographic assessment for the detection of hemodynamically important coronary-artery stenoses and that use...

FFR and iFR work together seamlessly on one system console, utilizing the same pressure wire and providing dual modality. With the introduction of iFR, interventional cardiologists now have more choices; and with the flip of a switch, the iFR modality provides a …

2022年5月3日 · In contemporary practice, we use 2 methods to measure such gradients: fractional flow reserve (FFR), which measures the pressure gradient during hyperemia and across the entire cardiac cycle; and the so‐called resting indices (the most well known of which is instantaneous wave‐free ratio—iFR), which measure the pressure gradient without drug‐ind...

2022年5月2日 · Functional evaluation of coronary artery stenoses using fractional flow reserve (FFR) is considered the gold standard given its relation to clinical outcomes. More recently, nonhyperemic pressure‐derived ratios are increasingly used preferentially over FFR as they eliminate the time, cost, and adverse effects of pharmacologic hyperemia.

Instantaneous wave free ratio (iFR) is another physiological index which can be obtained at rest without hyperemic stimulation. iFR is conceptually different from FFR, leading to lively scientific debate about this index. In this review article, the concept, differences and similarities of FFR and iFR are reviewed.

Both fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are used in routine clinical practice, following the results of large-scale clinical outcomes trials (DEFER [Fractional Flow Reserve to Determine the Appropriateness of Angioplasty in Moderate Coronary Stenosis], FAME [Fractional Flow Reserve versus Angiography for ...

Long-term data on safety and efficacy of instantaneous wave-free ratio (IFR) vs fractional flow reserve (FFR) in guiding percutaneous coronary intervention (PCI) is lacking. This study sought to evaluate the 5-year clinical outcomes of IFR- vs FFR-guided PCI in a real-world setting.

More recently, the instantaneous wave-free ratio (iFR) and other resting pressure–derived indices that do not require hyperemia have emerged as alternatives to FFR. This article summarizes the concepts of FFR, iFR, and other resting indices and the current evidence supporting their use.

2025年2月1日 · FFR, iFR, CFR and IMR are physiologic measurements used to evaluate the function of epicardial coronary arteries and the microvascular coronary circulation. Strong evidence supports the use of FFR and iFR to guide revascularization in stable epicardial CAD and non-culprit lesions in acute MI.

2013年2月6日 · iFR systematically overestimates FFR, with wide limits of agreement that would often alter management decisions. In individual patients, iFR is not interchangeable with FFR. In VERIFY, a prospective study of 206 consecutive PCI patients compared with a retrospective analysis of 500 archived pressure recordings, Berry and colleagues showed that: