
An overview of FSH-FSHR biology and explaining the existing …
Follicle stimulating hormone (FSH) is a gonadotropin hormone secreted by anterior pituitary gonadotropic cells, is central to reproduction in mammals and its synthesis is regulated by …
Follicle-stimulating hormone receptor - Wikipedia
The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that interacts with the follicle-stimulating hormone (FSH) and represents a G protein-coupled …
卵泡刺激素及其受体的信号传递功能和相关疾病的研究进展-在线期 …
卵泡刺激素(FSH)是由垂体前叶促性腺激素细胞分泌的促性腺激素,与卵泡刺激素受体(FSHR)结合,刺激卵泡的生成和精子的发生,FSH或FSHR缺乏会导致男性精子减少以及 …
Mechanism of hormone and allosteric agonist mediated ... - Nature
2023年1月31日 · Follicle stimulating hormone (FSH) is an essential glycoprotein hormone for human reproduction, which functions are mediated by a G protein-coupled receptor, FSHR....
Nature子刊:黄荷凤院士团队揭示FSH调节胰岛素分泌和糖稳态新 …
2023年11月4日 · 该研究首次揭示了卵泡刺激素(Follicle-stimulating hormone,FSH)对胰岛素分泌的调控新机制,以及FSH升高是围绝经女性糖尿病易感性的重要诱因。 黄荷凤团队多年来 …
上海药物所与合作单位揭示促卵泡激素及小分子激动剂识别和激活 …
促卵泡激素(follicle-stimulating hormone,FSH)是由垂体分泌的一种糖蛋白激素,能够作用于性腺(睾丸或卵巢)组织特定靶细胞上的卵泡刺激素受体(FSHR),从而调控卵泡的成熟和排 …
Follicle-Stimulating Hormone Receptor: Advances and …
2018年1月1日 · Follicle-stimulating hormone (FSH) is produced in the pituitary and is essential for reproduction. It specifically binds to a membrane receptor (FSHR) expressed in somatic cells …
Follicle Stimulating Hormone Receptor ( FSHR ) - Springer
2018年1月1日 · FSH is synthesized and released by gonadotropic cells in the anterior pituitary in response to gonadotropin-releasing hormone (GnRH) from the hypothalamus. It consists of …
Atlas of Fshr expression from novel reporter mice - PubMed
2025年1月8日 · The FSH-FSHR pathway has been considered an essential regulator in reproductive development and fertility. But there has been emerging evidence of FSHR …
Structure-Function Relationships of the Follicle-Stimulating …
In this review, we describe the most important structural features of the FSHR intimately involved in regulation of FSHR function, including trafficking, dimerization, and oligomerization, ligand …