The FTD-FRS was completed by family members or caregivers, and Neurologists completed the 8-item Clinical Dementia Rating for Frontotemporal Lobar Degeneration (CDR-FTLD) scale (6 original domains plus Language and Behavior). The Alzheimer disease and FTD patients had equivalent disease severity level.

In order to better and more readily identify the behavioral symptoms in FTD, we have developed a new and original scale named DAPHNE. The primary aim of this prospective multicenter study was to test the validity and reliability of this new scale and then to investigate whether it could be helpful in diagnosing bvFTD and especially in ...

The Frontotemporal Dementia Rating Scale (FRS; Mioshi et al., 2010) is a novel staging tool that assesses disease severity in frontotemporal dementia (FTD) based upon functional dependence and behavioral changes.

There are two main types of FTD: behavioral FTD variant (bvFTD), characterized by a deterioration in social function, behavior, and personality; and primary progressive aphasias (PPA), characterized by a deficit in language skills.

Recommendation for clinical use: The European Reference Network for Rare Neurological Diseases strongly recommends the use the following scale as best clinical practice for the assessment and rating of Frontotemporal Dementia.

Objectives: To evaluate the ability of the FTD Rating Scale (FTD-FRS) to detect functional and behavioral changes in patients diagnosed with the behavioral variant of FTD (bvFTD), primary progressive aphasia (PPA), and Alzheimer disease (AD) after 12 months of the initial evaluation, compared to the Clinical Dementia Rating scale-frontotemporal ...

2023年12月25日 · Previous research in genetic frontotemporal dementia (FTD) has suggested that the FTD Rating Scale (FRS) may be a more sensitive measure of disease severity than the Clinical Dementia Rating scale plus National Alzheimer’s Coordinating Centre Frontotemporal Lobar Degeneration score (CDR+NACC FTLD).

The first manifestations of FTD are behavioral abnormalities. The aim of this study was to assess a behavioral scale of frontal lobe dysfunction and to determine a behavioral cutoff to diagnose early FTD and distinguish it from AD and VaD.

2024年3月6日 · Access up-to-date information on the Frontotemporal Dementia Rating Scale (FRS or FTD-FRS) described in ePROVIDE: copyright, licensing, scoring, translations.

The objectives of this study were to: (1) evaluate and compare how the FRS and CDR+NACC FTLD scales characterise disease stage and severity in the spectrum of presymptomatic and symptomatic genetic FTD, using cross-sectional data from the Genetic FTD Initiative (GENFI) cohort; (2) examine and compare longitudinal change in the scales using data ...