
Roles of the FabA and FabZ β-Hydroxyacyl-Acyl Carrier Protein ...
1996年11月1日 · Roles for FabA and FabZ in fatty acid biosynthesis. Both FabA and FabZ dehydratases function interchangeably in the cycles of fatty acid elongation up to 10 carbons. …
Crystal structure of FabZ-ACP complex reveals a dynamic seesaw …
2016年11月22日 · We present here a 2.55 Å crystal structure of type II FAS dehydratase FabZ in complex with holo-ACP, which exhibits a highly symmetrical FabZ hexamer-ACP3 …
一种不寻常的 3-羟酰基脱水酶 (FabZ) 的结构,来自具有意想不到 …
在这项研究中,我们对这种酶进行了表征,我们将其称为厌氧氨氧化特异性 FabZ(“amxFabZ”),以研究梯烷脂质未解决的生物合成途径。 我们发现 amxFabZ 显示出 …
FabA和FabZβ-羟酰基-酰基载体蛋白脱水酶在大肠杆菌脂肪酸生物 …
FabA和FabZ表现出广泛的重叠链长特异性。 FabZ脱水酶可有效催化短链β-羟酰基ACP和长链饱和和不饱和β-羟酰基ACP的脱水。 FabA对中链长度的β-羟酰基-ACP最为活跃,并且对短链和长 …
Structures of an unusual 3-hydroxyacyl dehydratase (FabZ) from a ...
2023年5月1日 · In this study, we characterize this enzyme, which we call anammox-specific FabZ (“amxFabZ”), to investigate the unresolved biosynthetic pathway of ladderane lipids.
Structural Basis for Catalytic and Inhibitory Mechanisms of β ...
2008年2月29日 · β-Hydroxyacyl-acyl carrier protein dehydratase (FabZ) is an important enzyme for the elongation cycles of both saturated and unsaturated fatty acids biosyntheses in the type …
β-Hydroxyacyl-acyl Carrier Protein Dehydratase (FabZ) from …
2016年2月23日 · To this end, we have cloned, expressed, and purified the β-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from both Francisella tularensis (FtFabZ) and Yersinia …
CDD Conserved Protein Domain Family: FabZ - National Center …
2020年10月2日 · FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third …
Roles of the FabA and FabZ β-Hydroxyacyl-Acyl Carrier Protein ...
There are two genes, fabA and fabZ, encoding β-hydroxyacyl-acyl carrier protein (ACP) dehydratases that function in the dissociated, type II fatty acid synthase system of Escherichia …
CDD Conserved Protein Domain Family: FabA_FabZ - National …
2020年10月2日 · FabZ is the primary dehydratase that participates in the elongation cycles of saturated as well as unsaturated fatty acid biosynthesis, whereas FabA is more active in the …
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