Intra- and inter-molecular regulation by intrinsically-disordered ...
2023年11月13日 · Caenorhabditis elegans PUF protein fem-3 binding factor-2 (FBF-2) partners with intrinsically disordered Lateral Signaling Target-1 (LST-1) to regulate target mRNAs in …
The Puf RNA-binding proteins FBF-1 and FBF-2 inhibit the …
2010年6月1日 · FBF-1 and FBF-2 (collectively FBF) are two nearly identical Puf-domain RNA-binding proteins that regulate the switch from mitosis to meiosis in the C. elegans germline. In …
The PUF RNA-binding protein, FBF-2, maintains stem cells without ...
2024年10月25日 · Here we report that an FBF-2 mutant protein that cannot bind to RNA, is nonetheless biologically active and maintains stem cells. This unexpected result challenges …
PUF family proteins FBF-1 and FBF-2 regulate germline stem and ...
2019年10月31日 · Through investigating the regulation of germline stem cells by two PUF family RNA-binding proteins FBF-1 and FBF-2 in C. elegans, we find that FBF-1 restricts …
Divergence of Pumilio/fem-3 mRNA Binding Factor (PUF) Protein ...
2012年2月2日 · Bioinformatics analysis shows that mRNAs associated with Caenorhabditis elegans fem-3 mRNA binding factor (FBF)-2 in vivo contain an upstream cytosine required for …
Intra- and inter-molecular regulation by intrinsically-disordered ...
2023年11月13日 · Caenorhabditis elegans PUF protein fem-3 binding factor-2 (FBF-2) partners with intrinsically disordered Lateral Signaling Target-1 (LST-1) to regulate target mRNAs in …
Bipartite interaction sites differentially modulate RNA-binding ...
2022年1月11日 · Here we focus on understanding how the essential partner protein, LST-1, modulates mRNA regulation by the PUF protein, FBF-2. LST-1 contains two nonidentical sites …
Diverse Roles of PUF Proteins in Germline Stem and Progenitor …
2020年2月6日 · This review summarizes the many roles of PUF-8, FBF-1, and FBF-2 in germline stem and progenitor cells (SPCs) and discusses the factors accounting for their distinct …
FBF-1 and FBF-2 Regulate the Size of the Mitotic Region in the …
2004年11月1日 · We propose that the divergent fbf genes and their regulatory subnetwork enable a precise control over size of the mitotic region. Therefore, fbf-1 and fbf-2 provide a paradigm …
The Puf RNA-binding proteins FBF-1 and FBF-2 inhibit the …
2010年6月1日 · FBF-1 and FBF-2 (collectively FBF) are two nearly identical Puf-domain RNA-binding proteins that regulate the switch from mitosis to meiosis in the C. elegans germline. In …