2003年7月12日 · Feline leukemia virus, a retrovirus, is a common infection of cats. It is the cause of more cat deaths, directly or indirectly, than any other organism and is widespread in the cat population. Disease Transmission. FeLV transmission …

Feline leukaemia virus is a gamma retrovirus affecting domestic and small wild cats. As with all retroviruses, FeLV is an enveloped RNA virus, which relies for its replication on a DNA intermediate. Using its reverse transcriptase activity, the RNA genome is reverse-transcribed into a DNA, which is usually integrated into the host's cell genome.

FeLV exposure results in a number of possible outcomes including solid immunity, transient viremia with latency and clearance and overwhelming persistent viremia. The outcome as for other infections is determined by virulence of the infecting strain, host immune responses and environmental exposure.

AZT is a nucleoside reverse transcriptase inhibitor; it can reduce plasma viral loads, increase CD4/CD8 ratios and improve clinical status, particularly in FIV-FeLV-infected cats with stomatitis or neurological disease; results have not been as favourable in FeLV-FeLV-infected cats, although some mild benefits have been reported.

Feline leukemia virus (FeLV) is one of the most common and important infectious diseases in cats, affecting between 2-3% of all cats in the United States and Canada. Infection rates are significantly higher (up to 30%) in cats that are ill or otherwise at high risk (see below).

FeLV: Transmitted primarily via saliva (grooming, bite wounds), queen to kittens. FIV: Transmitted primarily in saliva via bite wounds; queen to kittens is uncommon. Oral disease: 1 in 5 cats with stomatitis is retrovirus-positive; almost 1 in 5 cats with bite wounds or …

2022年2月8日 · Feline leukemia virus is a retrovirus in the family Oncovirinae. As a retrovirus, FeLV is an enveloped virus with a positive-sense single-stranded RNA genome, which relies on a double-stranded DNA intermediate (i.e. provirus stage) in its life cycle for replication (Baltimore classification group VI, (+)ssRNA-RT).

Feline leukemia virus, a retrovirus, is a common infection of cats. It is the cause of more cat deaths, directly or indirectly, than any other organism and is widespread in the cat population.

FeLV is a highly contagious virus spread primarily via saliva among cats in casual close contact. Mutual grooming, shared food/water bowls, and aggressive behaviors can be a means of transmission. Depending upon the age, health, and immune status of the cat exposed to the virus, the infection may become progressive, regressive, or be aborted.1,4.

2020年8月26日 · Feline leukaemia virus (FeLV) is a retrovirus of domestic cats worldwide. Cats lacking strong FeLV-specific immunity and undergoing progressive infection commonly develop fatal FeLV-associated disease. Many aspects of FeLV infection pathogenesis have been elucidated, some during more recent years using molecular techniques.