
Central amygdala micro-circuits mediate fear extinction - Nature
2021年7月6日 · Our findings identify CEA inhibitory microcircuits that act as critical elements within the brain networks mediating fear extinction. The survival of animals depends on their …
Encoding of conditioned fear in central amygdala inhibitory
2010年11月10日 · Using in vivo electrophysiological, optogenetic and pharmacological approaches in mice, we show that neuronal activity in the lateral subdivision of the central …
The Physiology of Fear: Reconceptualizing the Role of the Central ...
Fear can be defined as the neurophysiological processes that prepare an organism to perform innate or learned responses to cope with danger. In general, our understanding of the …
杏仁核神经环路在调控焦虑行为中的作用机制研究进展|焦虑|BLA|杏 …
2021年11月2日 · 焦虑障碍是一类以机体对外源性和内源性刺激表现出过度恐惧、焦虑或回避行为为特征的精神疾病(包括广泛性焦虑症、社交焦虑症、创伤后应激障碍、分离焦虑症、恐慌症 …
Neuronal circuits for fear and anxiety - Nature
2015年5月20日 · The amygdala nuclei involved in fear learning can be divided into two main sub-areas — the basolateral amygdala (BLA) and the central amygdala (CEA) — that …
Fear can be defined as the neurophysiological pro-cesses that prepare an organism to perform innate or learned responses to cope with danger. In gen-eral, our understanding of the …
Neuronal circuitry of fear conditioning and extinction
We found that fear conditioning induced differential changes in stimulus-evoked and spontaneous firing of distinct types of CEA neurons. Moreover, targeted pharmacological inactivation …
Encoding of conditioned fear in central amygdala inhibitory circuits
2010年11月11日 · Using in vivo electrophysiological, optogenetic and pharmacological approaches in mice, we show that neuronal activity in the lateral subdivision of the central …
A Neural Switch for Active and Passive Fear: Neuron - Cell Press
2010年8月26日 · Our findings identify a neural circuit in CeA that biases fear responses toward either passive or active coping strategies. Research over the past decades has consistently …
Persistent activation of central amygdala CRF neurons helps …
2020年1月22日 · In summary, we propose that CeA–CRF neurons reflect this persistent state of fear and through the modulatory actions of CRF signaling prevents the weakening of the fear …
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