In Klinefelter syndrome, there are two X chromosomes and a Y chromosome (XXY). In rare cases, additional X chromosomes (XXXY or XXXXY) may also be linked to Klinefelter …

常见染色体核型为：47，xxy， 嵌合型：46，xy/47，xxy。 其原因是精子或卵子在生长发育过程中，X染色体不分离所致。 克氏综合征患者由于存在一条额外的X染色体，往往存在男性 性腺功 …

This case series expands our knowledge of the prenatal presentation of 47, XXY by identifying first and second trimester fetal sonographic abnormalities. Prenatal identification of this …

Klinefelter syndrome (47, XXY karyotype) is the spectrum of phenotypic features resulting from a sex chromosome complement that includes two or more X chromosomes and one Y …

Klinefelter syndrome is a chromosomal disorder present in 1 out of 400 to 1,000 male newborns in Western populations. Two-thirds of affected newborns show a karyotype of 47,XXY. Few …

2023年9月1日 · I shall review the fertility aspects of the sex chromosome trisomies, XXY, XYY, and XXX, with special reference to the karyotype 45,X/47,XXX. Each has a ‘specific’ (but …

Among the 19 cases of confirmed fetal XXY, 14 elected pregnancy termination, and the rest five led to live birth. Four of the five babies (1 month, 5 months, 1 year, 1.5 years old, respectively) …

2024年10月31日 · 该研究以导致男性不育最常见的性染色体疾病——克氏综合征（核型47,XXY）为代表，系统揭示了额外的X染色体导致男性胎儿生殖细胞（Fetal germ cell, …

Cell-free DNA was extracted from maternal peripheral blood to have a high-throughput massively parallel sequencing procedure. Cases with high-risk of fetal XXY were suggested to take …

XXY occurs when a male has an extra X chromosome in some or all cells of his body. About 1 out of every 660 males is born with XXY, and there about 300,000 with this condition in the U.S. …