Fibroblast growth factor 1 - Wikipedia
Fibroblast growth factor 1 (FGF-1) also known as acidic fibroblast growth factor (aFGF), is a growth factor and signaling protein encoded by the FGF1 gene. [5] [6] It is synthesized as a …
了不起的成纤维细胞生长因子(FGF)家族 - 知乎 - 知乎专栏
FGF1的功能主要是调节细胞周期、细胞分化、存活和细胞凋亡。 FGF1是惟一的可激活所有的成纤维细胞生长因子受体剪接变异体的成纤维细胞生长因子。 FGF4亚科： 由FGF4，5，6组成。 …
FGF1 Gene - GeneCards | FGF1 Protein | FGF1 Antibody
2024年12月25日 · FGF1 (Fibroblast Growth Factor 1) is a Protein Coding gene. Diseases associated with FGF1 include Common Peroneal Nerve Lesion and Overnutrition. Among its …
FGFR：信号通路与靶向药物 - 知乎 - 知乎专栏
成纤维细胞生长因子受体 （FGFR）包括FGFR1, FGFR2, FGFR3, FGFR4及FGFRL1 (缺少胞内激酶结构域），由不同基因编码，但结构功能相似，为单次跨膜蛋白，有胞外区，跨膜区，胞内 …
Cell Metabolism：FGF1破解胰岛素的“百年孤独” - 知乎专栏
外源性FGF1注射可以通过作用于脂肪细胞FGF受体（FGFR1）的方式来快速降低糖尿病小鼠模型的血糖水平。 FGF1能够通过抑制 HPA轴 （下丘脑 - 垂体 - 肾上腺轴），减少促肾上腺皮质 …
FGF/FGFR signaling in health and disease - Nature
2020年9月2日 · Fibroblast growth factors (FGFs) are broad-spectrum mitogens and regulate a wide range of cellular functions, including migration, proliferation, differentiation, and...
FGF1 fibroblast growth factor 1 [ Homo sapiens (human) ]
2025年2月8日 · FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, …
成纤维细胞生长因子 1（FGF1）基因 | MCE - MCE-生物活性 ...
该基因编码的蛋白质是成纤维细胞生长因子 (FGF) 家族的成员。 FGF 家族成员具有广泛的促有丝分裂和细胞存活活性，并参与多种生物过程，包括胚胎发育、细胞生长、形态发生、组织修复 …
The FGF family: biology, pathophysiology and therapy - PMC
Figure 1. structural features of fibroblast growth factors (FgFs). a | FGF1, showing its 12 antiparallel β-sheets and amino and carboxyl termini. b | The 18 FGFs, grouped according to …
Metabolic Messengers: fibroblast growth factor 1 - Nature
2022年6月9日 · FGF1 (or acidic FGF) is an autocrine/paracrine hormone historically identified as a mitogen that has recently garnered increasing attention as an anti-diabetic agent 1, 2, 3, 4. …