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2019年3月20日 · Here, we show that the blood protein fibrinogen induces spine elimination and promotes cognitive deficits mediated by CD11b-CD18 microglia activation. 3D molecular labeling in cleared mouse and human AD brains combined with repetitive in vivo two-photon imaging showed focal fibrinogen deposits associated with loss of dendritic spines independent...

FGG官网-全新独立外设品牌FGG，出品极致电竞装备，打造潮流外设产品。

Hosted dimerization: Proteins such as yellow fluorescent protein (YFP) with an N-terminal FGG peptide motif form dimers mediated by supramolecular interactions with cucurbit[8]uril (see scheme). The protein dimerization, which is observed by FRET and size-exclusion chromatography, can be reversed with methyl viologen as a bioorthogonal ligand ...

Hosted dimerization: Proteins such as yellow fluorescent protein (YFP) with an N‐terminal FGG peptide motif form dimers mediated by supramolecular interactions with cucurbit[8]uril (see scheme). The protein dimerization, which is observed by FRET and size‐exclusion chromatography, can be reversed with methyl viologen as a bioorthogonal ...

黄色荧光蛋白（英語： Yellow Fluorescent Protein ，缩写YFP）是一种绿色荧光蛋白（GFP）的变体 [1] ，能发出黄色 荧光（激发峰517nm，发射峰527nm） [2] ，从GFP变为YFP至少需要蛋白质序列上四个氨基酸残基（aa）发生改变，其中最重要的是203号位的苏氨酸变为酪氨酸 ...

2010年1月20日 · Ein Plätzchen zum Kuppeln: Proteine wie das gelb fluoreszierende Protein (YFP), die ein N‐terminales FGG‐Motiv tragen, dimerisieren unter Mitwirkung von supramolekularen Wechselwirkungen innerhalb ...

野生型GFP（wild type GFP, wtGFP）从一开始就引起了人们极大的兴趣，而且被用作新型的简单报告基因及体内标记，但GFP在异源生物体中的表达并非那么简单。 例如，研究人员很早就发现需要在较高的温度下孵育才能在细胞或生物体中表达GFP，并且wtGFP在37℃的热稳定性差。 这些都阻碍了它在转基因中的应用。 这些难题促使人们进一步筛选分离wtGFP的变体。 现在，人们已经找到了荧光强度更强且更耐热的变体。 这些变体多数为经突变的脱辅基蛋白，它们可防止 …

2015年1月13日 · The interplay of Phe-Gly-Gly (FGG)-tagged proteins and bivalent FGG-tagged penta(ethylene glycol) as guest molecules with cucurbit[8]uril (Q8) hosts is studied to modulate the supramolecular ...

2010年1月19日 · Hosted dimerization: Proteins such as yellow fluorescent protein (YFP) with an N-terminal FGG peptide motif form dimers mediated by supramolecular interactions with cucurbit[8]uril (see scheme). The protein dimerization, which is observed by FRET and size-exclusion chromatography, can be reversed with methyl viologen as a bioorthogonal ligand ...