Mitochondrial fission protein 1 (Fis1) was identified in yeast as being essential for mitochondrial division or fission and subsequently determined to mediate human mitochondrial and …

2024年12月25日 · FIS1 (Fission, Mitochondrial 1) is a Protein Coding gene. Diseases associated with FIS1 include Spinocerebellar Ataxia 12 and Cranial Nerve Disease. Among its related …

2022年4月27日 · FIS1 is a Type II integral membrane protein anchored to the mitochondrial outer membrane exposing an N-terminal domain comprised of two tetratricopeptide repeats (TPRs) …

2021年12月1日 · Fis1 pY38 promoted mitochondrial fission by recruiting the mitochondrial fission GTPase dynamin-related protein-1 (Drp1) to mitochondria. Fragmented mitochondria fueled …

2021年3月25日 · Mitochondrial fission protein 1 (Fis1) was identified in yeast as being essential for mitochondrial division or fission and subsequently determined to mediate human …

Fis1, a protein on the mitochondrial outer membrane, is thought to mediate mitochondrial fission. However, Fis1 null worms and mammalian cells only display mild fission defects but show …

Here, we show that hFis1‐mediated mitochondrial fragmentation occurs in the absence of Drp1 and Dyn2, suggesting that they are dispensable for hFis1 function. hFis1 instead binds to …

Fis1, a protein on the mitochondrial outer membrane, is thought to mediate mitochondrial fission. However, Fis1 null worms and mammalian cells only display mild fission defects but show …

2025年2月16日 · Our findings demonstrate that FIS1 upregulation, induced by lipotoxicity, exacerbates mitochondrial fragmentation through its interaction with DRP1, which leads to a …

Enables identical protein binding activity. Involved in several processes, including cellular response to thapsigargin; mitochondrial fragmentation involved in apoptotic process; and …