Flavr Savr (also known as CGN-89564-2; pronounced "flavor saver"), a genetically modified tomato, was the first commercially grown genetically engineered food to be granted a license for human consumption.

The genetically modified tomato went to U.S. market on May 21, 1994 known as the Flavr Savr. This transgenic tomato was no longer able to produce polygalacturonase(PG), which is an enzyme involved in

2021年7月4日 · The very first genetically modified food that was introduced into the market was a tomato called Flavr Savr. It was when Calgene, a California company, submitted the necessary documents for evaluation by the U.S. Food and Drug Administration (FDA) in 1992.

2021年7月17日 · Flavr Savr™ tomato developed by Monsanto Company was the first genetically engineered fruit to gain non-regulated status from APHIS and approval by the FDA 5,18.

2013年5月6日 · 1994: FLAVR SAVR Tomato. The FDA approved the sale of the first genetically modified food - the FLAVR SAVR tomato, deeming it as safe as conventionally-bred tomatoes. The FDA's decision on the FLAVR SAVR tomato - marketed by Calgene, Inc. of Davis, California - marked the first time the agency evaluated a food that was genetically engineered.

连续四年的田间环境安全性评价数据表明，番茄“FLAVR SAVR TM ”在农艺性状、杂草化、对非靶标生物和番茄田间节肢动物群落影响等方面与受体亲本无显著差异。 毒理学评价表明，未观察到聚半乳糖醛酸酶和NPTII蛋白对人和哺乳动物产生不良影响；营养学评价数据表明，番茄“FLAVR SAVR TM ”在各种微量元素含量、主营养成分含量等方面与受体亲本无显著差异。 番茄“FLAVR SAVR TM ”于1980～1992年完成田间环境安全性评价试验，于1992年、1995年、1996年分别 …

2021年9月23日 · 自1994年，世界所公认的第一种获得消费许可的商业种植的转基因作物——美国加尔金公司发布的番茄（Flavr Savr番茄）、到次年（1995年），美国又发布抗虫害功能的马铃薯，再到孟加拉国有望成为全球第一个种植转基因黄金大米的国家、阿根廷政府2020年10月9日 ...

The Flavr Savr tomato has increased storage life through suppression of the to-mato polygalacturonase(PG) gene, resulting from transformation of an antisense expres-sion cassette of the PG cDNA (pCGN1436) (Sheehy et al., 1988). Efficacious but non-commercial pCGN1436 transformation events contain multiple T-DNA insertions

Calgene noted this problem and began investigating how they could genetically engineer a tomato that could ripen on the vine and still be transported without being bruised or damaged. After over a decade of research, Calgene perfected the Flavr Savr, their genetically engineered tomato.

The Flavr Savr tomato was the first commercially grown genetically engineered food to be granted a license for human consumption. It was produced by the Californian company Calgene, and submitted to the U.S. Food and Drug Administration (FDA) in 1992.