Fluorine-18 (18 F, also called radiofluorine) is a fluorine radioisotope which is an important source of positrons. It has a mass of 18.0009380(6) u and its half-life is 109.771(20) minutes. It decays by positron emission 96.7% of the time and electron capture 3.3% of the time.

Fluorine-18 is the most frequently used radioisotope in positron emission tomography (PET) radiopharmaceuticals in both clinical and preclinical research. Its physical and nuclear characteristics (97% β+ decay, 109.7 min half-life, 635 keV positron ...

Fluor-18 für medizinische und Forschungs-Zwecke wird durch Zyklotronbestrahlung der jeweiligen Zielmoleküle (häufig (18O)-Wasser) produziert. Einen detaillierten und umfangreichen Überblick über die Fluor-18-Radiochemie, den 18 F-Markierungsstrategien und den Synthesewegen hin zu 18 F-markierten Molekülen haben Orit Jacobsen et al. in ...

2014年12月4日 · Fluorine-18 is the most frequently used radioisotope in positron emission tomography (PET) radiopharmaceuticals in both clinical and preclinical research.

Fluorine-18 is a radioisotope of the chemical element fluorine, which, in addition to the element-specific 9 protons, has 9 neutrons in the atomic nucleus, resulting in the mass number 19. As a positron-emitting radionuclide, 18 F is of practical importance in medical education (see below).

2021年10月14日 · Fluorine-18 atom is the radioactive isotope of fluorine with relative atomic mass 18.000938. The longest-lived fluorine radionuclide with half-life of 109.77 min. Follow these links to do a live 2D search or do a live 3D search for this compound, sorted by annotation score.

What affects SA of F18 ion? 1. Radioactivity, bombardment time and dose 2. Ions contamination. Higher radioactivity, higher SA? 3. Contamination from materials. Berridge M.S. et al., JLRC. 2009, 52, 543-548 Pike V. et al., Curr Radiopharm. 2009, 2, 1. How to measure specific activity of labeled molecules? Measure cold mass after probes decay.

2020年2月1日 · Fluorine-18 is one of the most widely used radionuclides for the production of radiopharmaceuticals for positron emission tomography (PET). The radiolabeling methods like nucleophilic, electrophilic, Cu mediated mechanisms or prosthetic groups are widely using to achieve high regioselective radiochemical yields.

The favorable chemical, physical, and nuclear characteristics of fluorine-18 (97% β + decay, 109.8 min half-life, 635 keV positron energy) make it an attractive nuclide for labeling and molecular imaging.

In this review we describe strategies for radiolabeling with fluorine-18, including classical fluorine-18 radiochemistry and emerging techniques for late stage fluorination reactions, as well as labeling technologies such as microfluidics and solid-phase radiochemistry.