The fluorenylmethoxycarbonyl protecting group (Fmoc) is a base -labile amine protecting group used in organic synthesis, particularly in peptide synthesis. [1] .

2018年7月16日 · 9-芴基甲氧基羰基保护基（9- fluorenylmethyloxycarbonyl, Fmoc） 、它经常用于通过氨基甲酸酯形成来保护胺基。 该保护基对酸性条件・氧化条件比较稳定、但是在温和的 …

Protecting groups (PGs) in peptide synthesis have inspired advanced design principles that incorporate “orthogonality” for selective C- and N-terminus and side-chain deprotections. The …

The many beneficial attributes of the Fmoc group, which have yet to be surpassed by any other Na-protecting group, allow very rapid and highly efficient synthesis of peptides, including ones …

New, stable amino-protecting reagents, Boc-DMT and Fmoc-DMT, were prepared, and found to be useful for the introduction of Boc and Fmoc groups into amines. Both the reagents can …

T. W. Green, P. G. M. Wuts, Protective Groups in Organic Synthesis, Wiley-Interscience, New York, 1999, 503-507, 736-739.

The Fmoc protecting group protects amines in synthesis, and is deprotected with bases such as secondary amines like piperidine. You might not expect it, but this group is similar to other …

在这里，我们报道了一种新的 Fmoc 脱保护方法，该方法在弱酸性条件下使用氢解合成 Z-Arg-Lys-酰氧基甲基酮 （Z-R-K-AOMK）。 这种新方法不仅对合成含有高反应性亲电试剂或其他类似 …

Some advantages of the Fmoc protective group are that it has excellent acid stability thus BOC and benzyl-based groups can be removed in its presence. It is readily cleaved, …

Currently, two protecting groups are commonly used in solid-phase peptide synthesis – Fmoc (9-fluorenylmethyl carbamate) and t-Boc (Di-tert-butyl dicarbonate). The use of Fmoc chemistry …