Erythrocyte Porphyrin (EP), Whole Blood - ARUP Lab
Elevated protoporphyrin (as in erythropoietic protoporphyria) and zinc coproporphyrin (usually associated with childbirth) can increase the apparent EP signal. A more specific test for free protoporphyrin is Porphyrins, Serum Total (0080429).
PEE - Overview: Porphyrins Evaluation, Whole Blood
Protoporphyrin fractionation is the main component of erythrocyte porphyrins. When total erythrocyte porphyrins are elevated, fractionation and quantitation of zinc-complexed and free protoporphyrin is necessary to differentiate the inherited porphyrias from other causes of elevated porphyrin levels.
Erythropoietic Protoporphyria - StatPearls - NCBI Bookshelf
2023年2月16日 · The normal total protoporphyrin level in erythrocytes is 80 mcg/dL, but in a patient with EPP, it is elevated up to 300 to 8000 mcg/dL. There is an increased percentage of erythrocyte metal-free protoporphyrin rather than zinc protoporphyrin.
Free erythrocyte protoporphyrin (FEP) I. Normal values for …
Since the early 1970s, measurement of free erythrocyte protoporphyrin (FEP) (by microextraction or by hematofluorometer) has been widely used to screen for lead poisoning and to evaluate microcytic red blood cell (RBC) disorders in children.
Erythrocyte Protoporphyrin - an overview | ScienceDirect Topics
Zinc protoporphyrin (ZPP), also called free erythrocyte protoporphyrin, is measured using a portable hematofluorometer as a point-of-care test using capillary (finger stick) samples.
Protoporphyrin (Blood) - Health Encyclopedia - University of …
The protoporphyrin test is used to diagnose blood problems caused by lead. The test can show lead exposure or lead poisoning. Lead poisoning is extremely dangerous because lead can damage organs throughout the body.
Laboratory methodologies for indicators of iron status: …
Erythrocyte protoporphyrin can be measured directly as zinc protoporphyrin, the form present in erythrocytes, or as free erythrocyte protoporphyrin after extraction.
Erythrocyte Protoporphyrin - an overview | ScienceDirect Topics
Erythrocyte Protoporphyrin is a compound synthesized in excess in patients with Erythropoietic Protoporphyria, leading to intense fluorescence in erythroid progenitor cells and increased levels causing photosensitivity and hepatic damage.
The Diagnosis and Management of Erythropoietic Protoporphyria
Erythrocyte protoporphyrin elevations are also evident in severe iron deficiency and lead poisoning. In EPP, the protoporphyrin is primarily free protoporphyrin, in contrast to iron and lead toxicity, in which predominantly Zn-protoporphyrin is found. 28 In EPP patients, ...
Free erythrocyte protoporphyrin (FEP) II. The FEP test is clinically ...
Microcytic red blood cells (RBC) are commonly encountered in clinical medicine and are caused by disorders of heme synthesis [usually iron deficiency anemia (IDA) or anemia of chronic disease (ACD)] or disorders of globin synthesis (usually thalassemia syndromes or HbE).