2022年4月25日 · FXTAS is a late-onset condition (occurs in people older than age 50) that develops in some men and women with an altered form of the Fragile X gene. Those with FXTAS do not have the intellectual or developmental disabilities common in Fragile X syndrome.

Although FXTAS affects individuals differently, the symptoms of the disorder are similar to those of Parkinson's or Alzheimer's disease, including memory loss, slowed speech, tremors, and a shuffling gait. 1 Some people will have many symptoms that appear quickly and …

Certain medications and therapies are helpful for treating symptoms of FXTAS and may help slow its progression. However, no treatment can stop FXTAS from progressing and none is considered a cure. Symptoms of FXTAS differ from person to person, and treatment should address a person's individual needs.

2012年5月30日 · The symptoms of FXTAS—memory loss, tremors, muscle stiffness or rigidity, a shuffling gait or walk, and slowed speech—are similar to Alzheimer's disease and Parkinson's disease symptoms. A characteristic of FXTAS is also ataxia, which means clumsiness of movement or loss of coordination that is not due to muscle weakness.

2021年8月24日 · FXTAS occurs in some people who have the premutation. The premutation is also related to fragile X-associated primary ovarian insufficiency (FXPOI) . People with 200 or more repeats in the promoter part of the gene have a …

2012年8月21日 · People with FXTAS are also at a higher lifetime risk of mood disorders, including major depressive disorder, anxiety disorder, and post-traumatic stress disorder. In addition, men with FXTAS are more likely to have high blood pressure than men without the FMR1 premutation.

2023年8月25日 · NICHD conducts and supports a variety of clinical research projects related to FXTAS. Find a Study on Fragile X-Associated Tremor and Ataxia Syndrome (FXTAS) | NICHD - Eunice Kennedy Shriver National Institute of Child Health and Human Development

Fragile X-Associated Tremor and Ataxia Syndrome (FXTAS) About. How is a change in the FMR1 gene related to FXTAS? What causes FXTAS? What are the symptoms of FXTAS? How do healthcare providers diagnose FXTAS? What are the treatments for FXTAS? NICHD Research Information; Find a Study; More Information. Other FAQs; Resources

2013年11月7日 · NICHD supports and conducts research on the diagnosis, treatment, management, prevention, and inheritance of Fragile X and its associated conditions, Fragile X-Associated Primary Ovarian Insufficiency (FXPOI) and Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS). All three conditions result from changes in the same gene on the X …

2019年8月29日 · Carriers of the FMR1 premutation—a mutation in the gene associated with the developmental disorder Fragile X syndrome—may have a higher risk for several health conditions, according to an analysis funded by the National Institutes of Health.