Anti-Fya can cause mild to severe (rare) hemolytic disease of the fetus and newborn. The occurrence of the Fyb antigen is 83% in Caucasians, 23% in Blacks, and 18.5% in Asians.

The Duffy glycoprotein is a receptor for chemicals that are secreted by blood cells during inflammation. It also happens to be a receptor for Plasmodium vivax, a parasite that invades red blood cells (RBCs) and causes malaria. RBCs that lack the Duffy antigens are relatively resistant to invasion by P. vivax.

2023年5月8日 · The Duffy blood group system is complex, highly immunogenic glycoprotein antigens found on the surface of Red Blood Cells (RBC), vasculature endothelial cells, alveolar epithelial cells, collecting tubules of the kidney, and on the surface of Purkinje cells in the brain, but are absent on the adult liver.

These reagents are designed to determine the presence of blood group antigens, antigens Fya (FY1), S (MNS3) and s (MNS4) on the surface of human red blood cells by manual method.

Bio-Rad Seraclone® Anti-Fya is used principally in the resolution of antibody problems or in family studies. The test principle is hemagglutination. The antibody in Seraclone® Anti-Fya (FY1)...

List the specific antigens desired on the order. Note: Antigen typings that require the use of an anti-human globulin reagent (eg, Fya, Fyb, s) will include the addition of a direct antiglobulin test, which will be performed at an additional charge. Examples of antigens routinely tested by the lab are listed below. -Fya/Fyb -C -c (little c) -E

Determine if the Fy (a) (FY1) antigen is expressed on the patient's red blood cells. To determine if the patient is heterozygous or homozygous for the Fy (a) antigen, FYB Antigen Typing - Patient (2007725) should also be ordered. Indicates whether a test has been approved by the New York State Department of Health.

Red Cross Anti-Fy' has been manufactured to meet or exceed FDA potency requirements. Each lot is tested against a panel of antigen positive red blood cells lo assure appropriate reactivity when...

Use to predict the expression of red blood cell (RBC) antigen specificities, aid in the selection of antigen-negative RBCs for transfusion, assess the risk of alloimmune hemolytic disease, or resolve conflicting serologic antibody results. For fetal testing, order Red Blood Cell Antigen Genotyping, Fetal (3016639) using a fetal specimen.

Fya/Fyb RBC Antigen Typing - RBC antigen typing is used to identify specific antigens on the red cell. Identification of specific red cell antigens of the father may be useful in assessing the risk of hemolytic disease of the newborn.