2004年3月1日 · Expert panels in the United States have recommended a 50-g, one-hour glucose challenge test (GCT) at 24 to 28 weeks of gestation followed by a 100-g, three-hour oral glucose tolerance test for...

Gestational diabetes mellitus (GDM) is glucose intolerance that is first recognized during pregnancy and suggests underlying beta cell dysfunction. 1 GDM affects up to 1...

2014年9月15日 · Gestational diabetes increases the risk of gestational hypertension, preeclampsia, cesarean delivery, and developing diabetes later in life. There is debate about the diagnosis and...

Serum tumour markers alpha fetoprotein (AFP), beta human chorionic gonadotropin (bHCG), and lactate dehydrogenase (LDH) represent valuable tools for the clinical management of testicular germ cell tumours (GCTs) [1].

2024年10月8日 · Treatment for children with central nervous system germ cell tumors (GCT) depend upon the specific tumor type. Options include radiation therapy, chemotherapy, surgery (in various combinations) and stem cell rescue. Get detailed information about GCTs in this clinician summary.

2023年3月30日 · Tumor markers in CNS germ cell tumors (GCTs) include human chorionic gonadotropin (HCG) and alpha fetoprotein (AFP), which have significant diagnostic implications, as elevation of either one leads to clinical diagnosis of non-germinomatous GCTs without histopathological confirmation, justifying intensified chemotherapy and irradiation.

2018年5月23日 · A critically important component of advanced GCT management is to ensure proper chemotherapy dosing to maximize patient outcomes. The standard dose for etoposide is 500 mg/m 2 per cycle and for cisplatin is 100 mg/m 2 per cycle in both the bleomycin, etoposide, and cisplatin and etoposide and carboplatin regimens.

2010年6月7日 · A significantly elevated serum AFP can establish the diagnosis of a mixed GCT in a patient whose histopathologic diagnosis is pure seminoma because seminomas do not produce AFP. However, borderline elevated values should be interpreted cautiously.

2021年3月1日 · GCTs are one of the few malignancies for which specific biochemical markers have been identified: human chorionic gonadotropin (HCG) and alfa-fetoprotein (AFP). Due to their specificity and sensitivity they constitute formidable tools in the diagnosis and monitoring of treatment for GCTs.

We evaluated the effectiveness of beta-human chorionic gonadotropin (β-hCG) and Alpha-fetoprotein (AFP) in Romanian children with (para)gonadal tumors and cysts, determining their accuracy in detecting malignancy, tumor-type, stage, …