2024年12月25日 · GDF3 (Growth Differentiation Factor 3) is a Protein Coding gene. Diseases associated with GDF3 include Microphthalmia/Coloboma 6 and Microphthalmia, Isolated 7. …

Growth differentiation factor-3 (GDF3), also known as Vg-related gene 2 (Vgr-2) is protein that in humans is encoded by the GDF3 gene. [5] GDF3 belongs to the transforming growth factor …

The GDF3 gene provides instructions for making a protein that is part of the transforming growth factor beta (TGFβ) superfamily, which is a group of proteins that help control the growth and …

GDF3 is either a bi-functional TGF-beta ligand, or, more likely, that it is a BMP inhibitor that can artificially activate Nodal signaling under non-physiological conditions. GDF3 regulates …

该基因编码 TGF-β (转化生长因子-β) 蛋白质超家族的分泌配体。 该家族的配体结合各种 TGF-β 受体，导致调节基因表达的 SMAD 家族转录因子的募集和激活。 编码的前原蛋白经过蛋白水解 …

2006年1月15日 · We show that GDF3 is an inhibitor of its own subfamily, blocks classic BMP signaling in multiple contexts, interacts with BMP proteins and is expressed specifically in the …

GDF3 is a member of the TGF-β1/bone morphogenetic protein family of growth factors that may also have NODAL-like activity (88–90). FIGURE 141-4 . Klippel–Feil anomaly of the cervical …

2023年1月18日 · To prevent extensive fibrosis and maintain cardiac contractility, a better understanding of fibrotic scar formation is needed. In a recent study, Masurkar et al. identified …

2022年12月9日 · 在这些因子中，TGF-β（转化生长因子-β）家族的成员 GDF3（生长分化因子 3）在缺血心脏中显着上调。 专门富含 GDF3 的条件培养基通过刺激激活素受体样激酶，诱导 …

2023年11月23日 · GDF3 inhibits the growth of breast cancer cells and promotes the apoptosis induced by Taxol. Expression pattern of growth/differentiation factor 3 in human and murine …