Glial fibrillary acidic protein (GFAP) is a protein that is encoded by the GFAP gene in humans. [5] It is a type III intermediate filament (IF) protein that is expressed by numerous cell types of the central nervous system (CNS), including astrocytes [6] and ependymal cells during development. [7]

Glial fibrillary acidic protein (GFAP) is an intermediate filament structural protein involved in cytoskeleton assembly and integrity, expressed in high abundance in activated glial cells. GFAP is neuroprotective, as knockout mice are hypersensitive to traumatic brain injury.

Glial Fibrillary Acidic Protein (GFAP) is a major protein found in the astrocytic cells of the brain, and it is considered a marker of astrogliosis, which is a characteristic feature of multiple sclerosis (MS) lesions.

2024年12月25日 · GFAP (Glial Fibrillary Acidic Protein) is a Protein Coding gene. Diseases associated with GFAP include Alexander Disease and Canavan Disease . Among its related pathways are Signaling by ERBB4 and Selective autophagy .

GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.

2022年2月3日 · Glial fibrillary acidic protein (GFAP) levels reflect the clinical severity and extent of intracranial pathology after traumatic brain injury (TBI).

The GFAP gene provides instructions for making a protein called glial fibrillary acidic protein. This protein is a member of the intermediate filament family of proteins. Intermediate filaments form networks that provide support and strength to cells.