The Nobel Prize in Chemistry 2008 was awarded jointly to Osamu Shimomura, Martin Chalfie and Roger Y. Tsien "for the discovery and development of the green fluorescent protein, GFP"

2008年10月8日 · This year’s Nobel Prize in Chemistry rewards the initial discovery of GFP and a series of important developments which have led to its use as a tagging tool in bioscience. By using DNA technology, researchers can now connect GFP to other interesting, but otherwise invisible, proteins.

2008年10月8日 · Green fluorescent protein bags the biggest gong in science. Aequorea victoria, source of the green fluorescent protein. Credit: G. OCHOCKI/SCIENCE PHOTO LIBRARY. The molecule responsible for a...

In its light-emitting organs resides the green fluorescent protein, GFP, which glows intensely under ultraviolet light. GFP now revolutionizes the life sciences, and the scientists responsible for its development have been awarded this year’s Nobel Prize in Chemistry.

2008年10月8日 · Nature Chemistry - The 2008 Nobel Prize for Chemistry has been awarded to Osamu Shimomura, Martin Chalfie and Roger Tsien for the discovery and development of the so-called green fluorescent ...

Osamu Shimomura painstakingly isolated GFP from hundreds of thousands of jellyfish, characterized the chromophore and elucidated the mechanism of Aequorean bioluminescence. Martin Chalfie expressed the protein in E. coli and C. elegans, and Roger Tsien developed a palette of fluorescent proteins that could be used in a myriad of applications.

2009年7月15日 · It can make tumors, amyloid plaques from Alzheimer′s disease, or pathogenic bacteria equally visible. Ground-breaking contributions in this field have resulted in the 2008 Nobel Prize for Chemistry being awarded to Osamu Shimomura, Martin Chalfie, and Roger Tsien. The Nobel Laureates describe their research first-hand.

2008年10月28日 · A complementary DNA for the Aequorea victoria green fluorescent protein (GFP) produces a fluorescent product when expressed in prokaryotic (Escherichia coli) or eukaryotic (Caenorhabditis elegans) cells.

Discovery of green fluorescent protein (GFP) (Nobel Lecture) Discovery of green fluorescent protein (GFP) (Nobel Lecture) Angew Chem Int Ed Engl. 2009;48(31):5590-602. doi: 10.1002/anie.200902240. Author Osamu Shimomura 1 Affiliation 1 …

The native green fluorescent protein (GFP), first so named by Morin and Hastings (1971 ab), from the jellyfish Aequorea victoria (Shimomura et al., 1962) contains 238 amino acids (Prasher et al., 1992).