
Green fluorescent protein - Nature Chemistry
2008年10月8日 · The very aptly named green fluorescent protein — or GFP as it is almost universally known — is a barrel-shaped protein made up of 238 amino acids.
These GFP-like proteins allow the monitoring in time and space of an ever-increasing num-ber of phenomena in living cells and organisms like gene expression, protein localization and dynamics, protein-protein interactions, cell division, chromosome replication and organiza-tion, intracellular transport pathways, organelle inheritance and biogene...
GFP: from jellyfish to the Nobel prize and beyond - PubMed
On December 10, 2008 Osamu Shimomura, Martin Chalfie and Roger Tsien were awarded the Nobel Prize in Chemistry for "the discovery and development of the green fluorescent protein, GFP". The path taken by this jellyfish protein to become one of the most useful tools in modern science and medicine is …
The Nobel Prize in Chemistry 2008 - NobelPrize.org
The Nobel Prize in Chemistry 2008 was awarded jointly to Osamu Shimomura, Martin Chalfie and Roger Y. Tsien "for the discovery and development of the green fluorescent protein, GFP"
In 1988, Martin Chalfie heard about GFP for the first time, and realised that its ability for independent fluorescence could perhaps make it an ideal cellular beacon for the model organisms he studied. Using molecular biological techniques, Chalfie succeeded in introducing the gene for GFP into the DNA of the
Discovery of Green Fluorescent Protein (GFP) (Nobel Lecture)
2009年7月15日 · Ground-breaking contributions in this field have resulted in the 2008 Nobel Prize for Chemistry being awarded to Osamu Shimomura, Martin Chalfie, and Roger Tsien. The Nobel Laureates describe their research first-hand. Trip the light fantastic: The green fluorescent protein (GFP) is an invaluable tool for biochemical and medicinal research.
荧光蛋白为他们三个赢得诺贝尔奖,也为人类带来希望之光_绿色
2020年1月18日 · 绿色荧光蛋白(green fluorescent protein, GFP)作为生物化学示踪剂,在当今生命科学和医学研究中相当于现代的电脑和互联网,你无法想象科学家没有了这个GFP,就像你无法想象现在的世界没了电脑和互联网一样。
Great glowing jellyfish! It's the Nobel Prize in Chemistry
2008年10月8日 · The green fluorescent protein (GFP) has revolutionized medical and biological science by providing a way to track the activity of individual proteins within a living...
Discovery and development of the green fluorescent protein, GFP…
2010年2月3日 · GFP combines the properties of a conventional chromophore/fluorophore with the added bonus of being able to be used as a reporter molecule in recombinant DNA-based technologies. For example, a fluorescence analytical signal can be obtained from the GFP fused to other proteins capable of specifically recognizing a target analyte.
Green fluorescent protein takes Nobel Prize - Chemistry World
2008年10月8日 · The 2008 Nobel Prize in Chemistry has been awarded jointly to Japanese scientist Osamu Shimomura and US researchers Martin Chalfie and Roger Tsien, for the discovery and development of the green fluorescent protein (GFP).