Cryo-EM structure of human glucose transporter GLUT4
2022年5月13日 · GLUT4 is the primary glucose transporter in adipose and skeletal muscle tissues. Its cellular trafficking is regulated by insulin signaling. Failed or reduced plasma …
Cryo-EM structure of human glucose transporter GLUT4 - PMC
GLUT4 is the primary glucose transporter in adipose and skeletal muscle tissues. Its cellular trafficking is regulated by insulin signaling. Failed or reduced plasma membrane localization of …
GLUT4 - Wikipedia
GLUT4 is the insulin -regulated glucose transporter found primarily in adipose tissues and striated muscle (skeletal and cardiac). GLUT4 is distinctive because it is predominantly stored within …
连发2篇！女神颜宁等团队解析了GLUT4结构及发现GLUT3抑制剂
2022年5月13日，清华大学闫创业及普林斯顿大学颜宁共同通讯在 Nature Communications 在线发表题为“ Cryo-EM structure of human glucose transporter GLUT4 ”的研究论文，该研究报告了 …
Current understanding of glucose transporter 4 expression and ...
GLUT4 mediates the effects of insulin, or insulin-like growth factor on regulations of cognition, memory, behavior, motor activity and seizures. GLUT4 positive neurons are responsible for …
Cryo-EM structure of human glucose transporter GLUT4
2022年5月13日 · GLUT4 is the primary glucose transporter in adipose and skeletal muscle tissues. Its cellular trafficking is regulated by insulin signaling. Failed or reduced plasma …
RCSB PDB - 7WSM: Cryo-EM structure of human glucose transporter GLUT4 ...
2022年1月30日 · Failed or reduced plasma membrane localization of GLUT4 is associated with diabetes. Here, we report the cryo-EM structures of human GLUT4 bound to a small molecule …
Molecular Dynamics Simulation Studies of GLUT4: Substrate-Free …
2010年12月3日 · GLUT4 is sequestered into intracellular vesicles in unstimulated cells and translocated to the plasma membrane by various stimuli. Understanding the structural details …
Cryo-EM structure of human glucose transporter GLUT4
2022年5月13日 · Here, we report the cryo-EM structures of human GLUT4 bound to a small molecule inhibitor cytochalasin B (CCB) at resolutions of 3.3 Å in both detergent micelles and …
Cryo-EM structure of human glucose transporter GLUT4.
GLUT4 is the primary glucose transporter in adipose and skeletal muscle tissues. Its cellular trafficking is regulated by insulin signaling. Failed or reduced plasma membrane localization of …