2020年12月14日 · Today, the U.S. Food and Drug Administration approved a first-of-its-kind intentional genomic alteration (IGA) in a line of domestic pigs, referred to as GalSafe pigs, which may be used for...

4 天之前 · Doctors in China have become the first to report details about a transplant of a genetically modified pig liver into a human. The liver was transplanted last year into a person who was brain-dead ...

2024年7月21日 · Learn how one family’s choice to donate a body for pig kidney research could help change transplants. Research on pig-to-human organ transplants, or xenotransplantation, has yielded a surprising benefit for people with red meat allergies caused by the bite of a lone star tick. Read more about the latest in organ transplant research.

2024年2月29日 · Four of the pigs are pregnant with cloned pig embryos that were genetically modified. The other three are suckling litters of modified piglets. "This is the farrowing facility where the...

Summary of the genetically modified pig models for human diseases. Genetic modification of livestock became a reality when transgenic rabbits, sheep and pigs were first produced by pronuclear deoxyribonucleic acid (DNA) microinjection (Fig. 1 A) (Hammer et al., 1985).

2024年12月2日 · In this study, we generated transgenic pigs expressing human CD47 (hCD47) and CD55 (hCD55) in α1,3-galactosyltransferase KO/β-1,4-N-acetyl-galactosaminyl transferase 2 KO/cytidine...

2020年12月22日 · There's a new, genetically modified pig in town, with uses for medical products and devices. The genetic change eliminates a sugar called alpha-gal, which is highly allergenic for a small group.

2025年3月21日 · The shortage of donors is a major challenge for transplantation; however, organs from genetically modified pigs can serve as ideal supplements1,2. Until now, porcine hearts and kidneys have been ...

Genetically modified pigs hold great promise in xenotransplantation. Therefore, genetically modified pigs can become cell, tissue and organ donors, providing a solution to severe shortage of organ donors. Advances in genetic engineering have made it possible to modify the xenograft donor genome in virtually unlimited ways.

2025年3月7日 · In experiments with pig hearts transplanted into the abdomens of five baboons, this treatment allowed the transplanted hearts to survive for up to 2.5 years.