Transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. GTPases are active when bound to GTP and inactive when …

A GTPase is an enzyme that facilitates the conversion of guanosine triphosphate (GTP) to guanosine diphosphate (GDP). It plays a crucial role in regulating various cellular processes …

Small GTPase is a kind of GTP-binding protein commonly found in eukaryotic cells. It plays an important role in cytoskeletal reorganization, cell polarity, cell cycle progression, gene …

Keywords: Translation, Ribosome, GTPase, Rbg1, Rbg2, Tma46, Gir2. Introduction. The developmentally regulated GTP-binding (DRG) proteins are a family of highly conserved …

The remarkable versatility of the GTPase cycle as a widespread regulatory mechanism for numerous biological processes reflects the structural diversity of the GTPases, GEFs, GAPs …

2016年6月15日 · The canonical regulators of Rho GTPases — guanine nucleotide exchange factors, GTPase-activating proteins and guanine nucleotide dissociation inhibitors — are …

2002年12月12日 · We have seen how a simple Rho GTPase switch can potentially orchestrate this biological complexity, what is needed now is evidence of how and when they actually do.

GAPs (GTPase activating proteins) catalyse the return to the inactive GDP-state, by stimulating an otherwise low intrinsic GTPase activity. (B) Ras activation at the leading edge of …

At least two alternative mechanisms for activation of the oncogenic potential of GTPases have been found. Point mutations that reduce their GAP-stimulated GTPase activity would render …

2019年1月1日 · Small GTPase is a kind of GTP-binding protein commonly found in eukaryotic cells. It plays an important role in cytoskeletal reorganization, cell polarity, cell cycle …