Gangliocytoma is a rare type of central nervous system (CNS) tumor made up of mature neurons. The most common site is the temporal lobe of the brain, but they can arise anywhere in the CNS including the cerebellum, brainstem, floor of the third ventricle, and spinal cord. They are among the most frequent tumors associated with epilepsy.

2022年4月18日 · Gangliocytoma and pineocytoma are rare, benign (not cancerous) brain tumors. These are slow-growing tumors that healthcare providers typically treat with surgery and radiation therapy. Gangliocytoma tumors affect parts of your central nervous system (CNS). Pineocytoma tumors form in your pineal gland, a small organ located deep in your brain.

2009年10月23日 · Histologic hallmark of a gangliocytoma is a tumor with disorganized, variably cellular, non-infiltrative (well circumscribed) aggregates of large and small neurons (Fig. 18.10) and no glial component.

Gangliocytoma tumors, though relatively rare, present a complex puzzle within the realm of neurosurgery and oncology. These benign tumors originate from neuronal cells and can manifest in various parts of the central nervous system, including the brain and spinal cord.

2024年7月17日 · Gangliocytomas are rare indolent CNS tumors (WHO grade 1), primarily encountered in children and frequently discovered as the cause of epilepsy. They are considered one of the long-term epilepsy-associated tumors (LEATs).

2019年12月13日 · Ganglioglioma (WHO grade I) is a well-differentiated, slow-growing glioneuronal neoplasm composed of dysplastic ganglion cells (i.e., large cells with dysmorphic neuronal features, without the architectural arrangement or cytological characteristic of cortical neurons) in combination with neoplastic glial cells.

2016年10月4日 · Gangliocytoma appears on axi al T2-weighted (A) and fluid-attenuated inversion recovery (FLAIR) MRI (B) as a cystic right temporal lobe mass with mural nodule and subtle T2 hyperintensity. This noncontrast CT scan 15 months earlier from the same patient as in Fig. 19.1 shows a calcified mass in the right temporal lobe.

2017年2月23日 · We report a case with a pure gangliocytoma devoid of symptomatic endocrine secretion, not surrounded by pituitary endocrine tumour cells. Immunochemistry of the tumour was positive for hypothalamic growth hormone releasing hormone (GHRH) and pituitary hormones, such as GH and ACTH.

2016年6月14日 · Gangliocytomas and gangliogliomas are well-differentiated, slowly growing neuroepithelial tumors, composed of neoplastic, mature ganglion cells alone or in combination with neoplastic glial cells, respectively [1]. "Gangliogliomas" were first described by James Ewing in 1926 and adopted by Cyril B. Courville in 1930 [2].

A rare, mixed neuronal-glial tumor characterized by slow growth and irregular arrangement of neoplastic ganglion cells (large, multipolar dysplastic neurons) within stroma composed of non-neoplastic glial elements. Most commonly it occurs in temporal lobe, but it can be located throughout central nervous system.