GAPDH或G3PDH是甘油醛-3-磷酸脱氢酶（ glyceraldehyde -3-phosphate dehydrogenase ）的英文缩写。 GAPDH是 糖酵解 反应中的一个酶，广泛分布于各种组织中的细胞。 该酶是 糖酵解 反应中的一个酶，由4个30－40kDa的 亚基 组成，分子量146kDa。 该酶基因为管家（house keeping）基因，几乎在所有组织中都高水平表达，在同种细胞或者组织中的蛋白质表达量一般是恒定的，且不受含有的部分 识别位点 、佛波脂等的 诱导物质 的影响而保持恒定，故被广泛用 …

GAPDH, Tubulin, Actin 是WB实验中最常用的三种上样内参（loading control），因被认为表达水平受环境因素影响较小，在个体各个生长阶段的大多数或几乎全部组织中持续表达或变化很小，所以被称为 管家基因 （house-keeping genes），是WB实验中校正上样量、检测上样过程 ...

Glyceraldehyde 3-phosphate dehydrogenase (abbreviated GAPDH) (EC 1.2.1.12) is an enzyme of about 37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules.

2023年6月3日 · 在细胞核中，gapdh是参与细胞分裂的基因转录体的核心组成部分。gapdh与核酸结合，参与介导rna核输出，影响mrna的稳定性和dna损伤的修复。更有趣的是，gapdh可以在端粒上找到，在那里它直接与端粒dna结合。

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a glycolytic enzyme whose role in cell metabolism and homeostasis is well defined, while its function in pathologic processes needs further elucidation. Depending on the cell context, GAPDH may ...

2025年3月16日 · HIV-1 Rev interacting protein, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells. The interaction of Rev with GAPDH is increased by RRE

GAPDH 或G3PDH是 甘油醛-3-磷酸脱氢酶 （ glyceraldehyde-3-phosphate dehydrogenase ）的英文缩写。GAPDH是 糖酵解 反应中的一个酶，广泛分布于各种组织中的 细胞 。 该酶广泛存在于众多生物体中，并且在细胞中含量丰富，占总蛋白的10%-20%。

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has long been recognized as an important enzyme for energy metabolism and the production of ATP and pyruvate through anaerobic glycolysis in the cytoplasm. Recent studies have shown that GAPDH has multiple functions independent of its role in energy m …

Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is one of the most prominent housekeeping proteins and is widely used as an internal control in some semi-quantitative assays. In addition to glycolysis, GAPDH is involved in several cancer-related ...

3-磷酸甘油醛脱氢酶(glyceraldehyde-3-phosphate dehydrogenase,GAPDH)一直以来被认为是一种只分布在细胞质中、仅在糖酵解过程中起关键作用的酶.但是近年来,越来越多的研究表明GAPDH是一种多功能蛋白,且在细胞核、细胞质、生物膜上均有定位.如在细胞核内,GAPDH参与tRNA出核 ...