The GATA transcription factor family consists of six DNA-binding proteins (GATA1-6) that regulates transcription of DNA due to their ability to bind to the DNA sequence "GATA" which can therefore affect different diseases.

Gene ID: 829425, updated on 18-Sep-2024. Encodes a member of the GATA factor family of zinc finger transcription factors.

Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes (By similarity). By similarity

UniProt is the world's leading high-quality, comprehensive and freely accessible resource of protein sequence and functional information.

This review focuses on an essential GATA2 enhancer (+9.5) and how +9.5 mutants inform basic and clinical/translational science. Recent findings +9.5 is essential for HSPC generation and function during development and hematopoietic regeneration. Human +9.5 mutations cause immunodeficiency, myelodysplastic syndrome and acute myeloid leukemia.

IbGATA24 可以与组成型光形态发生 9-5a (COP9-5a) 相互作用。 IbCOP9-5a 的过度表达通过调节 ABA 和活性氧 (ROS) 的积累增强了干旱和盐胁迫的抗性。 这些结果表明 IbGATA24 与 IbCOP9-5a 相互作用在非生物胁迫耐受

GATA转录因子是一类广泛存在于真核生物中的转录因子,在植物光响应调控,叶绿素合成,细胞分裂素响应以及碳,氮代谢等生物学过程中发挥重要作用,这些生物学过程与作物产量息息相关,对GATA家族的研究可以为作物增产提供一定的理论基础.GATA转录因子具有特殊的锌指结构,而且根据前人对拟南芥,蓖麻,水稻等植物的研究发现,锌指结构的大部分氨基酸位点在大部分成员中是高度保守的.本研究主要对GATA转录因子的特异结构,分类,进化分析以及生物学功能进行论述.通过 …

2023年12月2日 · GATA transcription factors are type IV zinc-finger proteins that play key roles in plant growth and responses to environmental stimuli. Although these proteins have been studied in model plants, the related studies of GATA gene family under abiotic stresses are rarely reported in grapevine (Vitis vinifera L.).

2021年8月16日 · GATA transcription factors (TFs) are widespread eukaryotic regulators whose DNA-binding domain is a class IV zinc finger motif (CX 2 CX 17–20 CX 2 C) followed by a basic region. We identified 262...

GATA transcription factors are zinc finger DNA-binding proteins that play crucial roles in various biological processes, including hematopoiesis. Among GATA family proteins, GATA-1, GATA-2, and GATA-3 are essential for hematopoiesis. GATA-1 functions to promote development of erythrocytes, megakaryocytes, eosinophils, and mast cells.