In molecular biology, a RING (short for Really Interesting New Gene) finger domain is a protein structural domain of zinc finger type which contains a C 3 HC 4 amino acid motif which binds two zinc cations (seven cysteines and one histidine arranged non-consecutively).

2022年8月30日 · The RING (really interesting new gene) finger (RNF) protein, containing the RING domain, exerts E3 ubiquitin ligase that mediates the covalent attachment of ubiquitin (Ub) to target proteins.

Gene Ring Named South Bend Central's top athlete in 1947...3-yr basketball performer...also played football and baseball, captaining teams in all 3 sports as senior...All-State basketball player...played for 2 HOF coaches, John Wooden and Bob Primmer...3-yr regular at Indiana Univ...MVP in '51...Balfour award winner that year...also starred in ...

RING型含有C3HC4结构的RING（Really Interesting New Gene）结构域，不生成E3-Ub中间体，而是直接将泛素从E2转移至底物。 RBR（RING-between-RING）型含有两个 RING域（RING1和RING2）和一个RING间（In-Between RING，IBR）结构域。

2024年12月25日 · This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex.

2024年12月25日 · RNF2 (Ring Finger Protein 2) is a Protein Coding gene. Diseases associated with RNF2 include Luo-Schoch-Yamamoto Syndrome and Non-Specific Syndromic Intellectual Disability . Among its related pathways are Transport of the SLBP independent Mature mRNA and PIP3 activates AKT signaling .

The RNF40 gene (also called BRE1B, RBP95, Staring, and KIAA0661) encodes an RING finger-type E3 ligase that monoubiquitylates histone H2B at lysine 120. In this review, we summarize the current knowledge of RNF40 gene structure and function, focusing on its role in H2B monoubiquitylation, DNA damage repair, apoptosis, cancer development, and ...

One of these proteins is the Really Interesting New Gene (RING), which has been studied extensively due to its structure and functions such as apoptosis, neddylation, and its role in ubiquitination. The RING domain is a cysteine-rich domain known to …

RING 指形蛋白包括在 SCF 和 VCB 样 E3 复合体中发现的 Hrt1/Roc1/Rbx1 蛋白、后期促进复合体的 APC1 组分、Cbl 家族蛋白、MDM2 和许多其他经证实具有 E3 连接酶活性、结合 E2 或参与泛素化的蛋白。

2024年10月6日 · 苗期和分蘖期接种稻瘟病菌后，突变体 osring113 相比野生型更敏感，真菌生物量更大，而 OsRING113 过表达系相反。 osring113 对白叶枯病菌也更敏感，过表达系更抗病。 几丁质处理后，相比日本晴， osring113 中活性氧 (ROS)积累受抑制，过表达系中ROS积累增加。 与这些表型一致，防卫相关基因 OsNAC4 的表达在突变体中下调但在过表达系中上调，丝裂原活化蛋白激酶包括OsMPK6和OsMPK3的激活在突变体中受抑制但在过表达系中增加。 这些结 …