2024年11月13日 · Our data points to a mechanism of post-transcriptional mitochondrial regulation in muscle via mitochondrial mRNA stabilization, offering insights into how exercise enhances …

Gene knock out or loss-of-function increases muscle weight and cross-sectional area (CSA). Increase in muscle weight (A) and fiber or muscle CSA (B) after gene knock out differs across …

2019年5月3日 · Each muscle gene set represents either the up- or downregulated genes from a single comparison within a gene expression study. The studies included human or murine …

2015年10月9日 · Based on this muscle expression compendium, we present the largest study to date of gene expression in human skeletal muscle related to aging. We address the concerns …

2023年9月13日 · A recent study published in Cell by the Millay lab reports on an elegant strategy to expand the repertoire of lentiviral (LV) vectors from being the main delivery tool for ex vivo …

2018年5月22日 · To identify muscle hypertrophy candidate genes we conducted a systematic review to identify genes whose experimental loss or gain-of-function results in significant …

These gene expression distinctions partly explain the genetic basis for skeletal muscle specialization, and they may help to explain skeletal muscle susceptibility to disease and …

Myostatin (MSTN), a member of the transforming growth factor-β superfamily, can negatively regulate the growth and development of skeletal muscle by autocrine or paracrine signaling. …

2025年3月18日 · During myogenesis, muscle stem cells exhibit DNA damage response (DDR) features, which are essential for myoblast differentiation and skeletal muscle regeneration. Ho …

2024年2月13日 · New research from Northwestern University has uncovered a previously unexplored relationship between a gene critical to immune cells and the establishment and …