Discovery of novel geranylgeranyl reductases and …
2018年12月28日 · Geranylgeranyl reductase (GGR) is a flavin-containing redox enzyme that hydrogenates a variety of unactivated polyprenyl substrates, which are further processed …
Identification of OsGGR2, a second geranylgeranyl reductase
2018年1月30日 · Geranylgeranyl reductase (GGR) is an essential enzyme for Toc production that catalyzes the reduction of geranylgeranyl pyrophosphate and geranylgeranyl-chlorophyll....
A geranylgeranyl reductase homolog required for cholesterol …
2025年3月11日 · Underlying the differences in cholesterol intermediate production among these myxobacteria is our discovery of a previously unknown bacterial C-24 sterol reductase (Bsr) …
Insights into substrate specificity of geranylgeranyl reductases ...
Digeranylgeranylglycerophospholipid reductase (DGGR) catalyzes the hydrogenation process that converts unsaturated 2,3-di-O-geranylgeranylglyceryl phosphate to saturated 2,3-di-O …
Unraveling the multiplicity of geranylgeranyl reductases in Archaea ...
2024年1月27日 · The crystal structure of GGR from S. acidocaldarius consists of three distinct domains: FAD binding, catalytic, and a C-terminal domain (Sasaki et al. 2011) (Fig. 2). This …
Structure and Mutation Analysis of Archaeal Geranylgeranyl Reductase ...
2011年6月17日 · The crystal structure of geranylgeranyl reductase (GGR) from Sulfolobus acidocaldarius was determined in order to elucidate the molecular mechanism of the catalytic …
Phylogenetic tree representing the diversity of the GGR family of ...
Phylogenetic tree representing the diversity of the GGR family of enzymes. The tree includes 1787 sequences of predicted GGRs from the InterPro database. Putative GGRs were selected …
Insights into Substrate Specificity of Geranylgeranyl Reductases ...
2010年12月3日 · DGGR is a member of the geranylgeranyl reductase family that is also widely distributed in bacteria and plants, where the family members are involved in the biosynthesis …
Vellore Engineering College chairman’s murder a result of decades …
2017年2月14日 · "To take revenge for the murder of Mahalingam, Kuppan for whom Maha entered the gang war with GGR family is suspected to have murdered GG Ravi," said a senior …
Discovery of novel geranylgeranyl reductases and characterization …
2018年12月28日 · We report the discovery of several novel GGRs exhibiting significant activity toward various polyprenyl substrates under mild conditions (i.e., pH 7.4, T = 37 °C), including …