
Insulin-like growth factor 1 - Wikipedia
Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role in childhood growth, and has anabolic effects …
生长激素与胰岛素样生长因子-1检测的临床意义 - 健康界
2021年9月2日 · 胰岛素样生长因子-1 (Insulin-like growth factor,IGF-1) 是一种在人体内生长激素(GH)刺激下产生的激素,当垂体前叶分泌GH进入血液循环时,几乎数分钟内GH即可以在 …
胰岛素样生长因子-1(IGF-1)有什么作用? - 知乎
胰岛素样生长因子-1 (IGF-1) 是一种激素,与生长激素一起(GH),有助于促进正常的骨骼和组织生长发育。 IGF-1检测可用于评估生长发育迟缓的青少年儿童。 IGF-1 主要由肝脏、骨骼肌和 …
打明星同款生长激素能不能抗衰老?——GH/IGF-1轴(上) - 知乎
IGF-1是一种既有胰岛素样合成代谢作用,又有促生长作用的多肽类生长因子,主要由肝脏合成,与其受体结合后启动两条信号传递链:RAS-RAF-MAPK和PI3K-PKB/AKT, 促进 有丝分裂 …
The GH/IGF-1 axis in ageing and longevity - PubMed
Secretion of growth hormone (GH), and consequently that of insulin-like growth factor 1 (IGF-1), declines over time until only low levels can be detected in individuals aged ≥60 years. This …
胰岛素样生长因子1 (IGF-1) 的临床意义与检测技术临床应用价值
2023年6月27日 · 胰岛素样生长因子1(Insulin-Like Growth Factor-1,IGF-1)是一种对细胞的增殖分化和人体的生长发育具有关键作用的调控因子。 临床上由生长激素(Growth …
Pediatric Implications of Normal Insulin-GH-IGF Axis Physiology
2024年4月4日 · The developmental establishment of GH control over the IGF1, IGFBP3 and IGFALS genes in early childhood initiates the dominance of the ternary complex formed by …
Central and peripheral regulation of the GH/IGF-1 axis: GHRH
2024年11月23日 · Among these, insulin-like growth factor 1 (IGF-1), produced primarily in the liver, mediates many of the growth-promoting effects of GH, acting both locally and …
Growth Hormone Signaling Pathway and Its Role in Health
2025年3月11日 · While the liver is the primary site for IGF-1 production, GH also acts on muscle, adipose tissue, and bone, influencing protein synthesis, fat metabolism, and skeletal …
Exploring the potential benefits of growth hormone co-treatment …
4 天之前 · While growth hormone (GH) is hypothesized to potentially enhance embryo quality, results of current basic and clinical researches remain inconclusive. This study assesses the …