Gigantism and oral manifestations. Gigantism is the childhood version of growth hormone excess and is characterized by the general symmetrical overgrowth of the body parts. Prognathic mandible, frontal bossing, dental malocclusion, and interdental spacing are the other features which may be seen in such individuals.

Gigantism (Greek: γίγας, gígas, "giant", plural γίγαντες, gígantes), also known as giantism, is a condition characterized by excessive growth and height significantly above average. In humans, this condition is caused by over-production of growth hormone in childhood.

Results: The most common facial dimorphisms involved the maxillo-facial district, with hypertrophy of the paranasal sinuses, thickening of the frontal bones, and protruding glabella, which may be associated with joint pain and clicks.

Acromegaly is a rare and underdiagnosed disease that results from the overproduction of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) [2, 3]. The disorder is known as acromegaly if it occurs during adulthood (around the age of 40), whereas gigantism is the childhood counterpart of the same disorder [4].

Overproduction of growth hormone causes excessive growth. In children, the condition is called gigantism. In adults, it is called acromegaly. Excessive growth hormone is almost always caused by a noncancerous (benign) pituitary tumor. Children develop great stature, and adults develop deformed bones but do not grow taller.

该疾病是由于人类在童年時期生产过多的 生长激素 [1]，常由垂体腺瘤导致 [2][3]，使得患者身高異於常人，達2.13米（7.0英尺）至2.72米（8.9英尺）。 巨人症可以是 遺傳性 的，也可以不是遺傳性的。 巨人症可以是先天的，也可以是後天的。 一般而言，如果巨人症是指 肢端肥大症，不會遺傳。 但有一些有巨人症症狀的病徵，如 馬凡氏症候群 則屬遺傳。 克氏综合征，也有巨人症的病徵，是先天性基因問題，但不會遺傳。 值得留意的是，一般所說的巨人症是指 肢端肥大症。 巨 …

2022年5月9日 · Gigantism, also called pediatric acromegaly and pituitary gigantism, is a very rare condition that happens when a child or adolescent has high levels of growth hormone (GH) in their body, which causes them to grow very tall. The pituitary gland normally produces GH, but a tumor on their pituitary can produce excess GH in gigantism.

2022年4月21日 · Gigantism and acromegaly are primarily caused by excess growth hormone. Most commonly, these conditions are caused by a benign, or noncancerous, tumor in the pituitary gland.

Acromegaly is a disease characterized by the gradual enlargement of the peaked (acral) parts of the body, including the nose, lips, tongue, lower jaw, hands, and feet and by hyperplastic alterations in the entire osseous system. Gigantism occurs before epiphyseal closure.

Gigantism is a condition resulting from an overproduction of growth hormone (GH), typically due to a benign tumour on the pituitary gland called an adenoma. This excessive secretion of growth hormone leads to accelerated growth rates and unusually tall stature.