We evaluated the efficacy and tolerability of Hachimi-jio-gan (HJG; 八味地黃丸 bā wèi dì huáng wán) and Gosha-jinki-gan (GJG; 濟生腎氣丸 jì shēng shèn qì wán), two traditional Japanese medicines, in 60 patients with lower urinary tract symptoms (LUTS) having cold sensitivity unresponsive to α1-blockers or antimuscarinic drugs.

Single oral administration of GJG (0.1-1 g/kg) exerted a dose-dependent inhibition on the established mechanical allodynia after paclitaxel injection, whereas the GJG-related herbal formulations HJG and RMG did not affect the established allodynia.

2022年3月20日 · Go-sha-jinki-Gan (GJG) is a traditional Japanese herbal medicine used for age-related symptoms. We have reported that GJG improved sarcopenia, chronic pain, and central nervous system function through suppression of tumor necrosis factor-alpha (TNF-α) production.

Peripheral neuropathy is a major dose-limiting side effect of the chemotherapeutic agent paclitaxel. This study examined whether the three related traditional herbal formulations, goshajinkigan (GJG; Niú Chē Shèn Qì Wán), hachimijiogan (HJG; Bā Wèi Dì Huáng Wán), and rokumigan (RMG; Liù Wèi Wán), wo …

2015年4月18日 · We evaluated the efficacy and tolerability of Hachimi-jio-gan (HJG; 八味地黃丸 bā wèi dì huáng wán) and Gosha-jinki-gan (GJG; 濟生腎氣丸 jì shēng shèn qì wán), two traditional Japanese medicines, in 60...

Change from baseline after 12 weeks of treatment with HJG or GJG. HJG GJG P Value # IPSS Total score: −2.6 ± 3.8: −4.3 ± 4.3: 0.113 Storage score: −1.1 ± 1.7: −2.1 ± 2.5: 0.151 Voiding score: −1.5 ± 3.3: ... GJG = Gosha-jinki-gan. IPSS=International Prostate Symptom Score. QOL = quality of life. BII = benign prostatic hyperplasia ...

2016年10月16日 · The most frequently used formula was goshajinkigan (GJG), followed by hachimijiogan (HJG) and keishibukuryogan. Thirteen of the 24 cases (54.2%) were prescribed aconite root-containing formulas including GJG and HJG.

2014年10月1日 · Goshajinkigan (GJG), a Kampo (traditional Japanese medicine) formula containing ten herbal medicines, has been shown to be effective for PTX-induced mechanical allodynia in mice [5]. Our previous...

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2016年4月19日 · In Japan, complex formulations containing traditional herbal medicines are widely utilized in treating LUTS patients. Among these, Hachimi-jio-gan (HJG) and Gosha-jinki-gan (GJG) have been shown to be efficient for LUTS when combined with standard drug treatments (antimuscarinic agents or α1-blockers).