Glaucine (also known as 1,2,9,10-tetramethoxyaporphine, bromcholitin, glauvent, tusidil, and tussiglaucin) is an aporphine alkaloid found in several different plant species in the family Papaveraceae, such as Glaucium flavum, [1] Glaucium oxylobum, and Corydalis yanhusuo, [2][3] and in other plants such as Croton lechleri in the family Euphorbia...

(S)-glaucine is an aporphine alkaloid that is (S)-1,2,9,10-tetrahydroxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo [de,g]quinoline in which the four phenolic hydrogens have been replaced by methyl groups.

Glaucine (O,O-Dimethylisoboldine) is an alkaloid extracted from Glaucium flavum that possesses various activities, including cough relief, bronchodilation, anti-inflammatory effects, analgesia, antipyretic properties, and anticancer effects. Glaucine acts as a selective and orally active inhibitor of phosphodiesterase 4 (PDE4), with a K i.

本品为外周抗胆碱药，除对平滑肌有解痉作用外，尚有阻断神经节及神经-肌肉接头的作用，对中枢的作用较弱。 眼部作用与阿托品相似，其散瞳、调节麻痹及抑制分泌的作用较阿托品强1倍，但持续时间短。 与阿托品兴奋大脑相反，本品表现为显著的镇静作用。 东莨菪碱的外周作用与阿托品相似，它对涎腺、支气管和汗腺分泌的抑制作用较阿托品强，对眼的散瞳和调节麻痹作用较阿托品迅速，但作用消失较快、对心脏、肠管和支气管平滑肌的作用较弱。 它也具有解除血管痉挛 …

Glaucine (O,O-Dimethylisoboldine) 是一种从 Glaucium flavum Crantz 中分离的生物碱，具有镇咳，支气管扩张和抗炎作用。 Glaucine 是一种选择性的，具有口服活性的磷酸二酯酶 4 (PDE4) 抑制剂，在人支气管和多形核白细胞中的 Ki 为 3.4 µM。

Glaucine is a non-narcotic antitussive agent with anti-inflammatory action but little analgesic action [57E]. Its d -isomer is an alkaloid from Glaucium flavum Crantz, a species of Papaveraceae [58E]. It is as effective as codeine but has a shorter duration of action [59C].

2021年11月1日 · Glaucine, first extracted from G. flavum, is a cough suppressant similar to codeine. In Eastern Europe, the hydrochloride and hydrobromide salts of its D-form have been used as cough suppressants. Synthetic glaucine is a racemic mixture with antitussive activity but without any significant activity on opioid receptors.

Glaucine (O,O-Dimethylisoboldine) 是一种从 Glaucium flavum Crantz 中分离的生物碱,具有镇咳,支气管扩张和抗炎作用。 Glaucine 是一种选择性的,具有口服活性的磷酸二酯酶 4 (PDE4) 抑制剂,在人支气管和多形核白细胞中的 Ki 为 3.4 µM。

中文名:海罂粟碱,英文名:Glaucine,CAS:475-81-0,化学式:C21H25NO4,分子量:355.43,密度:1.166±0.06 g/cm3 (20 ºC 760 Torr),熔点:246-247℃,沸点:488.45°C (rough estimate),折射率:1.5614 (estimate),MSDS.