
Glaucine - Wikipedia
Glaucine (also known as 1,2,9,10-tetramethoxyaporphine, bromcholitin, glauvent, tusidil, and tussiglaucin) is an aporphine alkaloid found in several different plant species in the family Papaveraceae, such as Glaucium flavum, [1] Glaucium oxylobum, and Corydalis yanhusuo, [2][3] and in other plants such as Croton lechleri in the family Euphorbia...
(S)-5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H
(S)-glaucine is an aporphine alkaloid that is (S)-1,2,9,10-tetrahydroxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo [de,g]quinoline in which the four phenolic hydrogens have been replaced by methyl groups.
Glaucine (O,O-Dimethylisoboldine) | PDE4抑制剂 | MCE
Glaucine (O,O-Dimethylisoboldine) is an alkaloid extracted from Glaucium flavum that possesses various activities, including cough relief, bronchodilation, anti-inflammatory effects, analgesia, antipyretic properties, and anticancer effects. Glaucine acts as a selective and orally active inhibitor of phosphodiesterase 4 (PDE4), with a K i.
东莨菪碱(有机化合物)_百度百科
本品为外周抗胆碱药,除对平滑肌有解痉作用外,尚有阻断神经节及神经-肌肉接头的作用,对中枢的作用较弱。 眼部作用与阿托品相似,其散瞳、调节麻痹及抑制分泌的作用较阿托品强1倍,但持续时间短。 与阿托品兴奋大脑相反,本品表现为显著的镇静作用。 东莨菪碱的外周作用与阿托品相似,它对涎腺、支气管和汗腺分泌的抑制作用较阿托品强,对眼的散瞳和调节麻痹作用较阿托品迅速,但作用消失较快、对心脏、肠管和支气管平滑肌的作用较弱。 它也具有解除血管痉挛 …
海罌粟鹼 | 475-81-0 - ChemicalBook
Glaucine (O,O-Dimethylisoboldine) 是一种从 Glaucium flavum Crantz 中分离的生物碱,具有镇咳,支气管扩张和抗炎作用。 Glaucine 是一种选择性的,具有口服活性的磷酸二酯酶 4 (PDE4) 抑制剂,在人支气管和多形核白细胞中的 Ki 为 3.4 µM。
Glaucine - an overview | ScienceDirect Topics
Glaucine is a non-narcotic antitussive agent with anti-inflammatory action but little analgesic action [57E]. Its d -isomer is an alkaloid from Glaucium flavum Crantz, a species of Papaveraceae [58E]. It is as effective as codeine but has a shorter duration of action [59C].
Phytochemistry and pharmacology of alkaloids from Glaucium …
2021年11月1日 · Glaucine, first extracted from G. flavum, is a cough suppressant similar to codeine. In Eastern Europe, the hydrochloride and hydrobromide salts of its D-form have been used as cough suppressants. Synthetic glaucine is a racemic mixture with antitussive activity but without any significant activity on opioid receptors.
Glaucine | 海罌粟鹼 | PDE | Calcium Channel | TargetMol
Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of human breast cancer cells by MMP-9 inhibitory activity, attenuating IκBα and NF-κB activities.
- 评论数: 10
海罂粟碱_用途_密度_熔点_CAS号【475-81-0】_化源网
Glaucine (O,O-Dimethylisoboldine) 是一种从 Glaucium flavum Crantz 中分离的生物碱,具有镇咳,支气管扩张和抗炎作用。 Glaucine 是一种选择性的,具有口服活性的磷酸二酯酶 4 (PDE4) 抑制剂,在人支气管和多形核白细胞中的 Ki 为 3.4 µM。
海罂粟碱(脱氢海罂粟碱)_化工百科 - ChemBK
中文名:海罂粟碱,英文名:Glaucine,CAS:475-81-0,化学式:C21H25NO4,分子量:355.43,密度:1.166±0.06 g/cm3 (20 ºC 760 Torr),熔点:246-247℃,沸点:488.45°C (rough estimate),折射率:1.5614 (estimate),MSDS.