
Glucagon-like peptide-1 receptor: mechanisms and advances in …
2024年9月18日 · The glucagon-like peptide-1 (GLP-1) receptor, known as GLP-1R, is a vital component of the G protein-coupled receptor (GPCR) family and is found primarily on the …
GLP1R Gene - GeneCards | GLP1R Protein | GLP1R Antibody
2024年12月25日 · GLP1R (Glucagon Like Peptide 1 Receptor) is a Protein Coding gene. Diseases associated with GLP1R include Insulinoma and Hyperglycemia. Among its related …
Glucagon-Like Peptide-1 Receptor Agonists - StatPearls - NCBI Bookshelf
2024年2月29日 · GLP-1 agonists (also known as GLP-1 receptor agonists, incretin mimetics, or GLP-1 analogs) represent a class of medications used to treat T2DM and, in some cases, …
GLP1R glucagon like peptide 1 receptor [ (human)] - National …
Gene ID: 2740, updated on 8-Feb-2025. This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose …
The structure and function of the glucagon-like peptide-1 receptor …
These multiple effects have generated a great deal of interest in the discovery of long-lasting agonists of the GLP-1 receptor (GLP-1R) in order to treat type 2 diabetes. This review article …
A free-energy landscape for the glucagon-like peptide 1 receptor GLP1R ...
The current study functionally characterizes GLP1R with special emphasis on ligand and cellular partner binding interactions and presents a free-energy landscape as well as a functional …
Glucagon Like Peptide 1 Receptor - an overview - ScienceDirect
The glucagon-like peptide-1 receptor (GLP-1R) is a significant therapeutic target for small molecule drug discovery given the therapeutic impact of peptide agonists in the diabetes sphere.
Full-length human GLP-1 receptor structure without orthosteric …
2020年3月9日 · GLP-1 acts on the GLP-1 receptor (GLP-1R) to lower blood glucose through enhanced glucose-dependent secretion of insulin, inhibition of glucagon secretion and slowed …
Glucagon-like peptide-1 receptor: mechanisms and advances in …
2024年9月18日 · Additionally, this paper explores the potential applications of GLP-1 receptor agonists (GLP-1RAs) in fields such as neuroprotection, anti-infection measures, the reduction …
Glucagon-like peptide-1 receptor expression and its functions …
2019年12月1日 · Glucagon-like peptide-1 receptor (GLP-1R) is an important pharmacological target for type 2 diabetes mellitus because it maintains glucose homeostasis and promotes β …
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