2023年7月4日 · Glucagonoma syndrome occurs due to the effects of elevated glucagon levels secreted by the tumor. The first case was described in 1942 by Becker et al. in a 45-year-old woman presenting with widespread dermatitis, weight loss, glossitis, and abnormal glucose tolerance associated with an islet cell neoplasm of the pancreas on autopsy specimen[1].

Glucagonoma is a very rare tumor of the alpha cells of the pancreas that results in the overproduction of the hormone glucagon. Typically associated with a rash called necrolytic migratory erythema, weight loss, and mild diabetes mellitus, most people with glucagonoma contract it spontaneously. [1] .

2024年8月6日 · Glucagonomas are rare functioning neuroendocrine tumors that secrete glucagon. This topic will review the clinical manifestations, diagnosis, and management of glucagonomas.

2023年9月13日 · Glucagonoma is a rare tumor that can release excess of a hormone called glucagon. When this happens, you develop several symptoms like a painful skin rash and weight loss, as well as symptoms of diabetes. Treatment includes medications to manage the symptoms of excess glucagon, surgery and certain cancer therapies. What is glucagonoma?

Glucagonoma is an extremely rare pancreatic α-islet cell tumor and is often accompanied by certain clinical symptoms including necrotizing migratory erythema (NME), diabetes, weight loss and anemia. The objectives of the current review were to ...

2023年4月7日 · The glucagonoma syndrome is caused by a glucagon-secreting pancreatic neuroendocrine neoplasm (panNEN)(glucagonoma). The syndrome includes: necrolytic migratory erythema, painful glossitis, cheilitis & stomatitis, weight loss, anemia, new-onset or worsening diabetes mellitus, hypoaminoacidemia, low zinc levels, deep vein thrombosis and depression.

2021年3月18日 · Glucagonoma is a form of pancreatic cancer that produces excessive levels of glucagon, which works with insulin to regulate blood sugar.

Glucagonoma syndrome is defined by the presence of an alpha-cell secreting tumour of the pancreas, elevated levels of glucagon, and a characteristic rash called necrolytic migratory erythema (NME). NME is usually a specific and often initial finding of glucagonoma syndrome, but it may occur in other …

A usually malignant, glucagon-producing neuroendocrine tumor arising from the pancreatic alpha cells. It may be associated with necrolytic erythema migrans, diarrhea, diabetes, glossitis, weight loss, malabsorption, and anemia. Almost 25% of patients experience thromboembolic complications, and 50% have liver metastases at the time of diagnosis.

Glucagonoma is a type of neuroendocrine tumour (NET) that starts in the pancreas. Its symptoms can be vague. See your GP if you are worried. Glucagonomas usually make the hormone glucagon. These are called functioning tumours. You might have symptoms caused by the increase in the amount of glucagon in your body.