2021年1月20日 · GntR家族转录调控因子是细菌中分布最为广泛的一类螺旋-转角-螺旋(helix-turn-helix,HTH)转录调控因子,此家族转录调控因子包含两个功能域,分别是N端的DNA结合结构域和C端的效应物结合结构域/寡聚化作用结构域。

摘要: GntR 家族转录调控因子是细菌中分布最为广泛的一类螺旋–转角–螺旋(helix-turn-helix ,HTH)转录调控 因子,此家族转录调控因子包含两个功能域,分别是N 端的DNA 结合结构域和C 端的效应物结合结构域/寡聚化作用结构域。

GntR家族转录调控因子是细菌中分布最为广泛的一类螺旋-转角-螺旋(helix-turn-helix,HTH)转录调控因子,此家族转录调控因子包含两个功能域,分别是N端的DNA结合结构域和C端的效应物结合结构域/寡聚化作用结构域。

2015年7月7日 · The GNTR family of transcription factors (TFs) is a large group of proteins present in diverse bacteria and regulating various biological processes. Here we use the comparative genomics approach to reconstruct regulons and identify binding motifs of regulators from three subfamilies of the GNTR fami …

2015年7月8日 · gntr转录因子（tfs）家族是一大类蛋白质，存在于各种细菌中并调节各种生物过程。 在这里，我们使用比较基因组学方法来重建调节子，并从GNTR家族的三个亚家族FADR，HUTC和YTRA鉴定调节子的结合基序。

2015年7月14日 · One of the most widespread family of transcription factors that regulates transcription through allostery on binding to metabolites is GntR family, which was first described by Haydon and Guest in 1991 2. The family was named after the gluconate operon repressor from Bacillus subtilis 3, 4.

In bacteria, GntR family transcription regulators are the widespread family of transcription factors. Members of this family consist of two functional domains, a conserved N-terminal DNA-binding domain that contains a typical helix-turn-helix (HTH) motif and a C-terminal effector-binding or oligomerization domain.

2022年12月8日 · 该研究揭示了GntR家族蛋白PmiR感知2-甲基异柠檬酸调节铜绿假单胞菌毒力的信号通路，有助于理解细菌感应环境信号与宿主反应之间的关系，为控制病原菌的感染提供了新思路。

In the present study, a GntR family transcription factor, encoded by the MSMEG_0535 (Ms0535) gene, was shown to be an isoniazid (INH) resistance regulator in Mycobacterium smegmatis. When the Ms0535 gene was overexpressed, cells showed a …

The GntR family of transcription factors (TFs) is a large group of proteins present in diverse bacteria and regulating various biological processes. Here we use the comparative genomics approach to reconstruct regulons and identify binding motifs of ...