2025年3月16日 · The Gene Ontology (GO) knowledgebase is the world’s largest source of information on the functions of genes. This knowledge is both human-readable and machine-readable, and is a foundation for computational analysis of large-scale molecular biology and genetics experiments in biomedical research.

GO describes concepts (also known as terms, or formally, classes) that are connected to each other via formally defined relations. The GO is designed to be species-agnostic to enable the annotation of gene products across the entire tree of life.

Many of these terms are from a jargon used for technical Go writing and are to some extent specially developed for Go journalism. Some authors of English-language Go materials avoid use of Japanese technical terms, and the way they are applied can differ in subtle ways from the original meanings.

GO annotations are meant to reflect the most up-to-date understanding of a gene product’s role. As biological knowledge advances, annotations for a particular gene product may be updated to align with new insights or adjustments in the ontology.

2019年4月12日 · GO terms consist of a GO ID, in the form GO:nnnnnnn, and a term string. The majority of GO terms have a textual definition, and many have synonyms, database cross-references and/or a comment. A piece of information linking a gene product to a GO term. Has four main parts: gene product, GO term, evidence code and reference.

QuickGO allows users to view and explore the Gene Ontology, Evidence and Conclusion Ontology, and GO annotations from various sources.

This web tool finds the significant GO terms shared among a list of genes from your organism of choice, helping you discover what these genes may have in common. View sample GO Term Finder results for sample gene list from Saccharomyces Genome Database (SGD).

The Gene Ontology (GO) is a collaborative effort to provide structured, standardized descriptions of gene products (protein or ncRNA) across biological databases. GO describes biological knowledge with respect to three aspects: Molecular function: activities performed by gene products (e.g. enzymatic activity).

Gene Ontology (GO) is a framework that provides a standard way to describe the roles of genes and their products in all species. Developed by the Gene Ontology Consortium, GO facilitates the systematic and consistent classification of gene functions, irrespective of the organism.

A , including UniProtKB curators, use GO terms to annotate gene products in a computationally tractable manner. UniProt lists the annotated GO terms in the 'Function' section; the GO terms from the 'Cellular component' category can also be seen in 'Subcellular location' section.