Gout: Treatment of flares - UpToDate
2024年9月20日 · Randomized trials have demonstrated that anakinra is as effective as standard-of-care therapies for the treatment of gout flares, although there may be an increased risk of rebound flares.
Treatment of gout flares - UpToDate
2023年11月30日 · Thus, agents inhibiting IL-1 action are an effective treatment for gout flares (see "Pathophysiology of gout"). Anakinra — Anakinra (100 mg daily, administered subcutaneously daily until flare resolution) is the preferred IL-1 antagonist for use in a gout flare because of its short half-life.
Treatment of gout flares - UpToDate
2023年8月24日 · Treatment of gout flare – For patients with a first or infrequent recurrent gout flare affecting one to two joints, we suggest intraarticular glucocorticoids if this treatment can be delivered in a timely manner .
Patient education: Gout (Beyond the Basics) - UpToDate
2024年1月18日 · The best treatment for gout flares is an antiinflammatory medication, such as nonsteroidal antiinflammatory drugs (NSAIDs), colchicine, or glucocorticoids. Medications are most effective when started early in the course of a flare.
acute gout - UpToDate
Treatment of gout flares …the prevention of recurrent gout after resolution of the gout flares are discussed separately. Several classes of antiinflammatory agents are effective for the treatment of gout flares , including systemic …
Gout: Clinical manifestations and diagnosis - UpToDate
2024年10月28日 · - Clinical diagnostic criteria-based diagnosis of a gout flare. Use of a clinical diagnostic rule; Role of imaging in diagnosis; Diagnosis of intercritical or tophaceous gout - Crystal demonstration in aspirates of synovial fluid or tophi - Histologic examination - Clinical diagnosis of intercritical gout; Classification criteria for gout ...
UpToDate
2024年10月28日 · Gout (monosodium urate [MSU] crystal deposition disease) is characterized biochemically by extracellular fluid urate saturation, which is reflected in the blood by hyperuricemia, with serum or plasma urate concentrations exceeding 6.8 mg/dL (approximately 400 micromol/L); this level of urate is the approximate limit of urate solubility . The ...
Gout: Clinical manifestations and diagnosis - UpToDate
- Clinical diagnostic criteria-based diagnosis of a gout flare. Use of a clinical diagnostic rule; Role of imaging in diagnosis; Diagnosis of intercritical or tophaceous gout - Crystal demonstration in aspirates of synovial fluid or tophi - Histologic examination - Clinical diagnosis of intercritical gout; Classification criteria for gout ...
Patient perspective: Gout - UpToDate
2024年12月10日 · This topic was written by an individual patient diagnosed with gout. It is intended to offer clinicians insight into the experience of a single individual from that individual's point of view, which may enhance clinical practice and health care delivery.
Diuretic-induced hyperuricemia and gout - UpToDate
The pathogenesis, epidemiology, and an overview of treatment of diuretic-induced hyperuricemia and gout are presented in this topic. The pathophysiology, clinical manifestations, diagnosis, and treatment of gout flares as well as the prevention of gout flares are discussed separately: