深圳大学医学部黄鹏教授团队Adv Mater：葡萄糖氧化酶用于癌症协同治疗的最新研究进展 …
2021年2月8日 · 该团队利用空心介孔有机硅纳米颗粒装载GOx和精氨酸，首次实现了基于GOx的活体肿瘤饥饿治疗，并通过产生的H2O2将精氨酸氧化产生NO气体，实现了肿瘤饥饿/气体的高 …
Diversified nanocarrier design to optimize glucose oxidase …
Starvation therapy (ST) utilizing glucose oxidase (GOx) has emerged as a promising strategy, specifically targeting tumor glucose consumption to disrupt nutrient supply. However, the …
Glucose Oxidase-Instructed Multimodal Synergistic Cancer Therapy
Over the past 3 years, glucose oxidase (GOx) has aroused great research interest in the context of cancer treatment due to its inherent biocompatibility and biodegradability, and its unique …
Recent advances in glucose oxidase-based nanocarriers for tumor ...
2023年10月1日 · Glucose oxidase (GOx) can specifically catalyze the conversion of β-d-glucose into gluconic acid and hydrogen peroxide (H 2 O 2) in the presence of oxygen, making it …
深圳大学黄鹏教授团队在葡萄糖氧化酶用于癌症协同治疗方面取得 …
2020年1月5日 · 该团队利用空心介孔有机硅纳米颗粒（HMON）装载GOx和精氨酸（ L-Arg），首次实现了基于GOx的活体肿瘤饥饿治疗，并通过产生的H 2 O 2 将 L-Arg氧化产生NO气体，实 …
Glucose oxidase and metal catalysts combined tumor synergistic …
2023年10月31日 · Glucose oxidase (GOx), a catalyst facilitating glucose consumption, has emerged as a critical therapeutic agent for ST. However, mono ST alone struggles to …
GOx催化连锁反应用于癌症协同治疗- X-MOL资讯
该团队受此启发，设计了一种新型的 可降解的GOx修饰的银纳米立方体（AgNC-GOx），用于癌症的类饥饿/金属离子协同治疗 （图1）。其中，GOx可催化肿瘤细胞内的葡萄糖发生降解反应， …
Focused starvation of tumor cells using glucose oxidase: A ...
2024年11月1日 · Starvation therapy targets the high metabolic demand of tumor cells. It primarily leans over the consumption of intracellular glucose and simultaneous blockade of alternative …
Recent Advances in Glucose-Oxidase-Based Nanocomposites for …
Glucose oxidase (GOx) can react with intracellular glucose and oxygen (O 2) to produce hydrogen peroxide (H 2 O 2) and gluconic acid, which can cut off the nutrition source of cancer cells and …
Glucose oxidase-instructed biomineralization of calcium-based ...
2023年7月11日 · GOx catalyzed glucose oxidation to generate H 2 O 2, which was further converted into highly toxic •OH by Mn 2+ to kill the cancer cells. GOx@MnCaP NPs were …